Results 51 to 60 of about 9,614 (265)

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

First JWST/NIRSpec Spectroscopy of O Stars in the Small Magellanic Cloud

The Astrophysical Journal Letters
Determining how much mass is removed by stellar winds is crucial to understanding massive star evolution and feedback. However, traditional spectroscopic diagnostics in the UV and optical are not sensitive enough to characterize weak stellar winds of OB ...
Armin Mang Román, Peter Zeidler, Wolf-Rainer Hamann, Lidia M. Oskinova, M. J. Rickard, S. Reyero Serantes, H. Todt, J. S. Gallagher III, D. Massa, D. Pauli, V. Ramachandran, E. Sabbi, A. A. C. Sander   +12 more
doaj   +1 more source

Infrared emission lines of Mg II in B stars [PDF]

Symposium - International Astronomical Union, 1994
Recently, Chang et. al. (1992) and Carlsson, Rutten and Shchukina (1992) (CRS) demonstrated the non-LTE formation mechanism behind the 12 μm Mg I emission lines (6g–7h, 6h–7i) observed in the solar spectrum (Murcray et. al., 1981). CRS stress the generality of this mechanism showing that it is a natural consequence of the recombination flow from the ...
T. A. Aaron Sigut, J. B. Lester
openaire   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

A Model of the C iv λ λ1548, 1550 Doublet Line in T Tauri Stars

The Astrophysical Journal
The C iv doublet in the UV has long been associated with accretion in T Tauri stars. However, it is still unclear where and how the lines are formed. Here, we present a new C iv line model based on the currently available accretion shock and accretion ...
Thanawuth Thanathibodee, Connor E. Robinson, Nuria Calvet, Catherine C. Espaillat, Caeley V. Pittman, Nicole Arulanantham, Kevin France, Hans Moritz Günther, Seok-Jun Chang, P. Christian Schneider   +9 more
doaj   +1 more source

Intensity Interferometry Observations of the Hα Envelope of γCas with MéO and a Portable Telescope

The Astronomical Journal, 2023
We report on observations of the extended environment of the bright Be star γ -Cas performed using intensity interferometry measurements within its H α emission line.
Nolan Matthews, Jean-Pierre Rivet, David Vernet, Mathilde Hugbart, Guillaume Labeyrie, Robin Kaiser, Julien Chabé, Clément Courde, Olivier Lai, Farrokh Vakili, Olivier Garde, William Guerin   +11 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Correction of UBV Photometry for Emission Lines

Open Astronomy, 2003
We investigate the effect on U,B,V magnitudes of the removal of emission lines from the spectra of some symbiotic stars and novae during their nebular phases.
Skopal A.
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

A Closer Look at the Origin of LINER Emission in Later-type Galaxies and Its Connection to Evolved Stars with a Machine Learning Classification Scheme

The Astrophysical Journal
Identifying the dominant ionizing sources in galaxies is essential for understanding their formation and evolution. Traditionally, spectra are classified based on their dominant ionizing source using strong emission lines and Baldwin, Phillips ...
Ahmad Nemer, Ivan Yu. Katkov, Joseph D. Gelfand, Changhyun Cho   +3 more
doaj   +1 more source