Results 51 to 60 of about 10,060 (266)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Identification of New Be Stars from LAMOST Data Release 11 Based on Deep Learning

The Astrophysical Journal Supplement Series
Be stars are rapidly rotating B-type stars that exhibit Balmer emission lines in their optical spectra, which makes them crucial for studying stellar evolution and circumstellar disk structures.
Lei Tan, Hui Deng, Tianhang Liu, Huanbin Chi, Yixing Chen, Ying Mei, Feng Wang   +6 more
doaj   +1 more source

A systematic assessment of the short-term X-ray behaviour of the γ Cas analogues

Astronomy & Astrophysics
Context. Overall, γ Cas analogues represent a class of OBe stars displaying bright and hard X-ray emission. This emission was recently determined to be the result of accretion onto a companion white dwarf (WD), which might possibly be a magnetic WD. Aims.
Webbe Robbie, Nazé Yaël, Webb Natalie A.   +2 more
doaj   +1 more source

Orbits and outflows of emission-line stars

, 2021
The optical spectra of some stars exhibit spectral lines in emission, which is characteristic of them having powerful radiatively driven winds. These stars are known as emission-line stars. In this thesis, I study the orbits and outflows of the most luminous and massive emission-line stars: Luminous Blue Variables and Wolf-Rayet stars.
openaire   +2 more sources

On the Formation of Balmer Emission Lines in the Model Envelopes of Be Stars [PDF]

Symposium - International Astronomical Union, 1994
We consider the formation of the Balmer emission lines and the decrement Hα/Hβ/Hγ, by solving the non-LTE problems in elementary regions of the envelope divided by equal line-of-sight velocities. These envelope-elements are characterized by different optical depths in the Balmer lines and by different dilution factors for the incident stellar radiation.
T. Kogure, S. Suzuki, M. Mon
openaire   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

First JWST/NIRSpec Spectroscopy of O Stars in the Small Magellanic Cloud

The Astrophysical Journal Letters
Determining how much mass is removed by stellar winds is crucial to understanding massive star evolution and feedback. However, traditional spectroscopic diagnostics in the UV and optical are not sensitive enough to characterize weak stellar winds of OB ...
Armin Mang Román, Peter Zeidler, Wolf-Rainer Hamann, Lidia M. Oskinova, M. J. Rickard, S. Reyero Serantes, H. Todt, J. S. Gallagher III, D. Massa, D. Pauli, V. Ramachandran, E. Sabbi, A. A. C. Sander   +12 more
doaj   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

A Model of the C iv λ λ1548, 1550 Doublet Line in T Tauri Stars

The Astrophysical Journal
The C iv doublet in the UV has long been associated with accretion in T Tauri stars. However, it is still unclear where and how the lines are formed. Here, we present a new C iv line model based on the currently available accretion shock and accretion ...
Thanawuth Thanathibodee, Connor E. Robinson, Nuria Calvet, Catherine C. Espaillat, Caeley V. Pittman, Nicole Arulanantham, Kevin France, Hans Moritz Günther, Seok-Jun Chang, P. Christian Schneider   +9 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source