Results 91 to 100 of about 3,929,924 (389)
Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
Radio emission from satellite-Jupiter interactions (especially Ganymede)
, 2017 Analyzing a database of 26 years of observations of Jupiter from the Nan\c{c}ay Decameter Array, we study the occurrence of Io-independent emissions as a function of the orbital phase of the other Galilean satellites and Amalthea.
Cecconi, B. +6 more
core +2 more sources
Pulsar optical emission as amplified synchrotron emission [PDF]
Monthly Notices of the Royal Astronomical Society, 1981 Pulsed optical emission has been observed from the Crab and Vela pulsars (Manchester and Taylor 1977). The pulse profile of the Crab pulsar has a main pulse and a strong interpulse separated by about 40% of the pulsar period; the peak of the main pulse is just resolved at 20 μs resolution; the spectrum is peaked at about 1014.8 Hz; the pulse profile is
openaire +4 more sources
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
F-Gases: Trends, Applications and Newly Applied Gases in the Czech Republic
Atmosphere, 2020 Emissions of fluorinated greenhouse gases (F-gases), which are used as replacements for ozone-depleting substances, have risen sharply since 1995.
Markéta Müllerová +2 more
doaj +1 more source
Experience with Carbon Taxes and Greenhouse Gas Emissions Trading Systems [PDF]
, 2018 Carbon taxes and emissions trading systems (ETSs) to limit emissions of greenhouse gases (GHGs) are increasingly common. At the end of 2015, 17 GHG ETSs were operational in 55 jurisdictions, and 18 jurisdictions collected at least one carbon tax.
Gallagher, Kelly Sims +6 more
core +2 more sources
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho +11 more
wiley +1 more source
Reflections on the Mechanisms to Protect Against Formation of Price Bubble in the EU ETS Market
Environmental Protection and Natural Resources, 2021 The rapid increases of European Union Allowance (EUA) prices and very high market volatility, resulting mainly from the growing role of speculative entities, can contribute to forming a price bubble. This may cause the market instability and could have a
Jeszke Robert, Lizak Sebastian
doaj +1 more source
Development of a low-maintenance measurement approach to continuously estimate methane emissions: a case study [PDF]
, 2016 The chemical breakdown of organic matter in landfills represents a significant source of methane gas (CH4). Current estimates suggest that landfills are responsible for between 3% and 19% of global anthropogenic emissions. The net CH4 emissions resulting
Allen, Grant +7 more
core +1 more source