Results 101 to 110 of about 12,407 (222)

In Vitro and in Vivo Studies of the Inhibitory Effects of Emodin Isolated from Polygonum cuspidatum on Coxsakievirus B4

Molecules, 2013
The lack of effective therapeutics for Coxsackievirus B4 (CVB4) infection underscores the importance of finding novel antiviral compounds. Emodin (1,3,8-trihydroxy-6-methylanthraquinone) is one of the natural anthraquinone derivatives obtained from the ...
Wei Hou, Fan Luo, Yuan-Yuan Liu, Hai-Rong Xiong, Liang-Jun Chen, Fei Wei, Zhao Liu, Hong Xiao, Zhan-Qiu Yang   +8 more
doaj   +1 more source

Emodin inhibits colon cancer tumor growth by suppressing tumor cell glycolysis through inhibition of NAT10-mediated PGK1 ac4C modification

Frontiers in Oncology
IntroductionInhibition of glycolysis represents a potent therapeutic approach for colon cancer. Emodin, a natural plant-derived compound with anticancer properties, has shown efficacy in cancer treatment.
Zhuoxin Wei, Zhuo Lv, Weimin Zhang
doaj   +1 more source

Poloxamer-Based Thermoreversible Gel for Topical Delivery of Emodin: Influence of P407 and P188 on Solubility of Emodin and Its Application in Cellular Activity Screening

Molecules, 2017
Emodin is a component in a Chinese herb, Rheum officinale Baill, traditionally used for diabetes and anticancer. Its poor solubility is one of the major challenges to pharmaceutical scientists.
Eunmi Ban, Mijung Park, Seonghee Jeong, Taekhyun Kwon, Eun-Hee Kim, Kiwon Jung, Aeri Kim   +6 more
doaj   +1 more source

Emodin inhibits the growth of hepatoma cells: Finding the common anti-cancer pathway using Huh7, Hep3B, and HepG2 cells.

, 2012
[[abstract]]Emodin—a major component of Rheum palmatum L.—exerts antiproliferative effects in cancer cells that are regulated by different signaling pathways.
Chin-Mu Hsu;Yu-An Hsu;Yuhsin Tsai;Fa-Kuen Shieh;Su-Hua Huang;Lei Wan;Fuu-Jen Tsai
core  

Emodin : a compound with putative antidiabetic potential, deteriorates glucose tolerance in rodents

, 2017
Emodin is found in remedies from Traditional Chinese Medicine. Since antihyperglycaemic action was observed in rodents, non-scientific sources advertise emodin intake as a natural cure for diabetes.
Kaplanian, Mairam, Abu Eid, Sameer, Fürnsinn, Clemens, Riedl, Rainer, Hackl, Martina Theresa, Scherer, Thomas, Adams, Michael, Torres-Gómez, Héctor Manuel, Luger, Anton   +8 more
core   +1 more source

Emodin Alleviates Lipid Accumulation and Renal Tubular Injury in Rats With DN via Inhibiting HIF-1α Expression

Frontiers in Bioscience-Landmark
Background: Our previous study verified that lipid nephrotoxicity mediated by hypoxia-inducible factor-1 alpha (HIF-1α) activation aggravates diabetic tubular injury.
Ying Wang, Xue Deng, Qian-wen Zhu, Jing Zhang, Zhi-wei Qian, Fang Gao, Shu-qin Zhan, Chao Wu, Lin Wang, Shu Li, Ze-bo Hu   +10 more
doaj   +1 more source

Emodin inhibits EBV reactivation and represses NPC tumorigenesis

, 2019
[[abstract]]Nasopharyngeal carcinoma (NPC) is a unique malignancy derived from the epithelium of the nasopharynx. Despite great advances in the development of radiotherapy and chemotherapy, relapse and metastasis in NPC patients remain major causes of ...
Wu, CC;Chen, MS;Cheng, YJ;Ko, YC;Lin, SF;Chiu, IM;Chen, JY
core   +2 more sources

Emodin Retarded Renal Fibrosis Through Regulating HGF and TGFβ–Smad Signaling Pathway

Drug Design, Development and Therapy, 2020
Fan Yang,1 Lu Deng,2 JinPeng Li,3 MuHu Chen,1 Ying Liu,1 YingChun Hu,1 Wu Zhong1 1Department of Emergency Medicine, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, People’s Republic of China; 2Department of Thyroid ...
Yang F, Deng L, Li J, Chen M, Liu Y, Hu Y, Zhong W   +6 more
doaj  

Aloe emodin inhibits the cytotoxic action of tumor necrosis factor

, 2007
We demonstrate the capacity of an herbal anthraquinone aloe emodin to reduce the cytotoxicity of the proinflammatory cytokine tumor necrosis factor (TNF) towards L929 mouse fibrosarcoma and U251 human glioma cell lines.
Harhaji, Ljubica M., Trajković, Vladimir, Danijela Maksimovic-Ivanic, Todorović-Marković, Biljana, Maksimović-Ivanić, Danijela, Biljana Todorovic-Markovic, Isaković,  Aleksandra, Ljubica Harhaji, Isaković, Aleksandra J., Dusan Popadic, Vladimir Trajkovic, Mijatović, Sanja, Trajković, Vladimir S., Sanja Mijatovic, Popadic, Dusan, Aleksandra Isakovic, Harhaji-Trajković, Ljubica   +16 more
core   +1 more source

The Effects Of Emodin On Macrophage-Cancer Cell Interaction

, 2016
Cancer results from mutations that cause alterations in cell function, growth and division. Malignant tumors formed of cancerous cells can lead to disruptions in systemic functions. A growing method of treatment for cancer is immunotherapy.
Fan, Wenxin
core   +1 more source