Results 141 to 150 of about 9,423 (183)
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Steroids, 2022
Aloe-emodin, known as a 3-hydroxymethyl-chrysazin, is one of anthraquinones mainly found in Rheum officinale Baill, Rheum palmatum L and Rheum tanguticum Maxim. Ex BALF. In recent studies, aloe-emodin possesses many pharmacological effects, including antitumor, antibacterial, antiviral, anti-inflammatory, cardiovascular protection, liver protection ...
Xin, Meng +4 more
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Aloe-emodin, known as a 3-hydroxymethyl-chrysazin, is one of anthraquinones mainly found in Rheum officinale Baill, Rheum palmatum L and Rheum tanguticum Maxim. Ex BALF. In recent studies, aloe-emodin possesses many pharmacological effects, including antitumor, antibacterial, antiviral, anti-inflammatory, cardiovascular protection, liver protection ...
Xin, Meng +4 more
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An Efficient Synthesis of O‐Methyl Protected Emodin Aldehyde and Emodin Nitrile.
ChemInform, 2003AbstractFor Abstract see ChemInform Abstract in Full Text.
Tarek A. Salama +2 more
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ChemInform Abstract: OXIDATION OF EMODIN ANTHRONE AND STEREOCHEMISTRY OF EMODIN BIANTHRONE
Chemischer Informationsdienst, 1976AbstractSynthetisches Emodin‐bianthron läßt sich in die Diastereomeren (Ia) (meso‐Form) und (Ib) (Racemat) trennen, die sich bei milder Oxidation unterschiedlich verhalten: Beide liefern ‐ bei Zutritt von Licht ‐ Hypericin (II) [im Dunkeln statt dessen jedoch Protohypericin (IV), das entsprechend bei Belichtung in (II) übergeht]; aus (Ia) entsteht ...
D. W. CAMERON +2 more
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Photochemistry and Phototoxicity of Aloe Emodin¶
Photochemistry and Photobiology, 2002Photochemical pathways leading to the phototoxicity of the aloe vera constituent aloe emodin were studied. The results indicate a photochemical mechanism involving singlet oxygen to be the most likely pathway responsible for the observed phototoxicity. Aloe emodin was found to efficiently generate singlet oxygen when irradiated with UV light (phidelta =
Peter, Vath +2 more
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A synthesis of emodin anthrone
Monatshefte f�r Chemie Chemical Monthly, 1991A novel high yield (74% overall) synthesis of five steps to prepare emodin anthrone, which serves as a valuable precursor of hypericin, was devised using the benzamideortho lithiation strategy for the key step.
Heinz Falk, Gerhard Schoppel
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Solubility of Emodin in Alcohols
Chinese Journal of Chemical Engineering, 2009Abstract Emodin is a kind of anthraquiones with pharmaceutical activities. The solubilities of emodin in ethanol, 1-octanol, and ethanol+1-octanol at different temperatures were measured using an analytical method. The solubility of emodin in these solvents increased with an increase in temperature.
Yangcheng LÜ +3 more
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Emodin-nicotinamide (1:2) cocrystal identified by thermal screening to improve emodin solubility
International Journal of Pharmaceutics, 2019Emodin (EM), an anthraquinone obtained from natural products, is known for many pharmacological activities. However, further evaluation and interpretation of toxicity or pharmacological activity of emodin are limited due to its poor aqueous solubility. We aimed to identify an emodin cocrystal with improved pharmaceutical properties.
Boosung Park +5 more
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Studies on the photostability and phototoxicity of aloe-emodin, emodin and rhein.
Die Pharmazie, 2002Aloe-emodin (1), emodin (2) and rhein (3) were found to be photolabile by visible (390-500 nm) light under aerobic conditions. The drugs 1, 2 and 3 were phototoxic in vitro when examined by the photohemolysis test under both oxygen and argon atmospheres, although the photohemolysis rate was markedly lower under anaerobic conditions.
F, Vargas +7 more
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Toxicology Mechanisms and Methods, 2004
The interaction of the dihydroxyanthraquinones, emodin (1), aloe-emodin (2), and rhein (3) with human serum albumin (HSA) has been studied through fluorescence spectroscopy. Quenching studies and the association constant of the anthraquinoid compounds 1, 2, and 3 in the presence of HSA were estimated. The binding and quenching studies suggest that only
F, Vargas, C, Rivas, M, Medrano
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The interaction of the dihydroxyanthraquinones, emodin (1), aloe-emodin (2), and rhein (3) with human serum albumin (HSA) has been studied through fluorescence spectroscopy. Quenching studies and the association constant of the anthraquinoid compounds 1, 2, and 3 in the presence of HSA were estimated. The binding and quenching studies suggest that only
F, Vargas, C, Rivas, M, Medrano
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Bioassay of Cathartics. I. Emodin Type
Journal of the American Pharmaceutical Association (Scientific ed.), 1952Tests of cathartics on the usual types of laboratory animals were reviewed. The unsatisfactory results obtained with the emodin type of drugs led to the development of a satisfactory method of bioassay on rats. The DD50 was determined by administration to a significant number of animals at several dosage levels; the consistency of the expressed fecal ...
A R, LATVEN, A B, SLOANE, J C, MUNCH
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