Results 41 to 50 of about 16,792 (294)

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source

Biocompatibility and Post-Marketing Surveillance Study of Emollient Plus Medical Device Cream Containing Oligofructans from Ophiopogon japonicus and Acetyl Heptapeptide-4 in Atopic Dermatitis Skin Care

Cosmetics
Emollients plus are defined as topical formulations containing active ingredients with no pharmacological effect. They are designed to target multiple mechanisms in AD pathophysiology.
Michał Rachalewski, Monika Pasikowska-Piwko, Renata Dębowska, Iwona Marczak, Karolina Lendzion, Hubert Godziątkowski, Robert Czarnomysy, Katarzyna Rogiewicz, Irena Eris   +8 more
doaj   +1 more source

Recommendations from a European Roundtable Meeting on Best Practice Healthy Infant Skin Care [PDF]

, 2016
Background European roundtable meeting recommendations on bathing and cleansing of infants were published in 2009; a second meeting was held to update and expand these recommendations in light of new evidence and the continued need to address uncertainty
Blume-Peytavi, U., Cork, M.J., Jenerowicz, D., Lavender, T., Ryumina, I., Stalder, J.F., Torrelo, A.   +6 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Newborn Skin Care is the Basis for Prevention of Atopic Dermatitis Development

Вопросы современной педиатрии, 2021
Healthy newborn skin care is challenging task. The basic principles of care should be taught to both medical staff and parents. This care is more crucial in children with atopic dermatitis who have abnormal skin acidity due to multifactorial exposure ...
Nikolay N. Murashkin, Leonid A. Opryatin, Roman V. Epishev, Alexander I. Materikin, Eduard T. Ambarchyan, Roman A. Ivanov, Dmitriy V. Fedorov, Daria S. Kukoleva   +7 more
doaj   +1 more source

NFATc1 supports imiquimod-induced skin inflammation by suppressing IL-10 synthesis in B cells [PDF]

, 2016
Epicutaneous application of Aldara cream containing the TLR7 agonist imiquimod (IMQ) to mice induces skin inflammation that exhibits many aspects of psoriasis, an inflammatory human skin disease.
A Johnston, A Kaczmarek, A Nast, A Nayak, A Roers, A Saxena, A Walter, A Yoshizaki, B Flutter, C Loh, C Mauri, C Scholz, E Hobeika, E Serfling, E Soutoglou, EC Rosser, EF Wagner, F Berberich-Siebelt, GJ Martinez, GK Perera, H Blumberg, H Li, H Vinter, H Vinter, HB Schonthaler, J Mehta, J Rengarajan, J Skrzeczynska-Moncznik, K Asadullah, K Guilloteau, K Miles, K Muhammad, K Yanaba, K Yanaba, K Yanaba, KE Kolodziej, L Dietz, M Dannappel, M Gilliet, M Hock, M Matsumoto, M Pasparakis, M Yang, MA Lowes, MC Bonnet, MP Schon, MP Schon, PA Blair, PG Hogan, PJ Hampton, PJ Mease, R Lande, R Weinlich, S Benoit, S Bhattacharyya, S Chuvpilo, S McManus, S Tenzer, T Nojima, U Distler, VC Kyttaris, WI Al-Daraji, WI Al-Daraji   +62 more
core   +2 more sources

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Cost Effectiveness of Emollients in the Prevention of Relapses in Atopic Dermatitis

Clinical, Cosmetic and Investigational Dermatology, 2020
Elise Cabout,1 Sebastien Eymere,1 Robert Launois,1 Flavia Aslanian,2 Charles Taïeb,3,4 Sophie Seité5 1Réseau d’évaluation en Économie de la Santé (REES), Paris, France; 2Epsom and St Helier University ...
Cabout E, Eymere S, Launois R, Aslanian F, Taïeb C, Seité S   +5 more
doaj  

New Cosmetic Formulation for the Treatment of Mild to Moderate Infantile Atopic Dermatitis

Children, 2019
Atopic dermatitis (AD) is a chronic cutaneous inflammatory disorder, characterized by skin barrier disruption. Dermacare is a new cosmetic formulation, which enhances moisturization, reinforces and repairs the skin barrier, and prevents cutaneous ...
Raúl de Lucas, Cristina García-Millán, Azahara Pérez-Davó, Esther Moreno, Pedro Redondo   +4 more
doaj   +1 more source

Instrumental and sensory characterisation of oleogels for cosmetic use [PDF]

, 2015
Oleogels are semisolid systems consisting of an oleogelator (gelling agent) and a lipophilic liquid phase. Despite having some distinct advantages (e.g. absence of preservatives or surfactants), the use of oleogels in cosmetic products is still sporadic.
Grant-Ross, Peter, Tamburic, Slobodanka, Utomo, Valerie, Varcin, Mustafa   +3 more
core