Results 41 to 50 of about 14,749 (291)

Gemcitabine, Docetaxel, Melphalan, Carboplatin as Part of Sequential Cycles of High‐Dose Chemotherapy With Autologous Hematopoietic Stem‐Cell Rescue for Multiply Relapsed/Refractory Pediatric Germ Cell Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Although most malignant germ cell tumors (GCTs) are highly curable with cisplatin‐based therapy, options for patients with multiply relapsed/refractory disease remain limited. For this population, we report the first pediatric use of gemcitabine, docetaxel, melphalan, and carboplatin (GemDMC) as part of sequential cycles of high‐dose ...
Maria Frost, Olayinka Okeleji, Amr Elgehiny, Douglas Harrison, Cynthia Herzog, Jeremy Connors, Demetrios Petropoulos, Priti Tewari, Dristhi Ragoonanan, Yago Nieto, Irtiza N. Sheikh   +10 more
wiley   +1 more source

CPX‐351 in High‐Risk Relapsed Pediatric Acute Leukemia: Real‐World Phase 1 Data Establishing the FDA‐Approved Dose

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Outcomes for pediatric relapsed/refractory (R/R) acute myeloid leukemia (AML) remain dismal. CPX‐351, a liposomal formulation of cytarabine and daunorubicin, may have less off‐target toxicities than traditional chemotherapies and has shown improved outcomes for adults with newly diagnosed therapy‐related AML.
Jonathan D. Bender, Lauren Pommert, Lori R. Backus, Andrea Bidwell, Courtney Blank, Erin H. Breese, Karen C. Burns, Adam Lane, Lynn H. Lee, Benjamin Mizukawa, Robin E. Norris, Maureen M. O'Brien, Daniel Peck, Christine Phillips, Thomas D. Ryan, Jennifer Young, Michael Absalon, John P. Perentesis   +17 more
wiley   +1 more source

Is colloidal oat an effective emollient ingredient for the prevention and treatment of atopic dermatitis in infants?

Journal of Dermatological Treatment
Background Atopic dermatitis (AD) is a chronic inflammatory skin condition characterized by barrier dysfunction and immune dysregulation, often leading to increased allergen penetration, sensitization, and secondary infections.
Joseph F. Fowler, Lin Ma, James Bergman, Paul Horowitz, Tina Lavender, Lawrence F. Eichenfield, Zoe Draelos, Simon G. Danby, Michael J. Cork   +8 more
doaj   +1 more source

Chronic eczema developing over skin treated for dermatophytosis in atopic patients -Importance of treating gently and intelligently

Indian Journal of Dermatology, 2022
A novel observation of chronic eczema developing over the skin of adequately treated lesions of tinea cruris/tinea corporis in six atopic individuals is being shared.
Shyam Verma, Ramkumar Ramamoorthy, J Vasani Resham   +2 more
doaj   +1 more source

Podoconiosis in East and West Gojam Zones, Northern Ethiopia [PDF]

, 2012
Background: Podoconiosis is a neglected tropical disease (NTD) that is prevalent in red clay soil-covered highlands of tropical Africa, Central and South America, and northern India. It is estimated that up to one million cases exist in Ethiopia.
A Tora, Abreham Tamiru, AP Oomen, AW Onapa, B Yakob, B Yakob, C Sikorski, E Ruberanziza, EW Price, EW Price, EW Price, F De Lalla, F Tekola, F Tekola, G Alemu, G Davey, G Davey, G Davey, G Davey, G Geshere Oli, G Mengistu, Gail Davey, H Kloos, John Owusu Gyapong, K Desta, K Desta, K Destas, L Ruiz, M Corachan, P Crivelli, S Wanji, Sara Tomczyk, Tsige Amberbir, Yordanos B. Molla   +33 more
core   +3 more sources

Emollients for eczema

Cochrane Database of Systematic Reviews, 2010
Reason for withdrawal from publication This protocol has been withdrawn as the team relinquished the title. A new review has been published by a new team: van Zuuren EJ, Fedorowicz Z, Christensen R, Lavrijsen A, Arents BWM. Emollients and moisturisers for eczema. Cochrane Database of Systematic Reviews 2017, Issue 2. Art. No.: CD012119.
Oranje, Arnold P., de Waard-van der Spek, Flora B., Ordonez, Clara, De Raeve, Linda, Spierings, Magda, van der Wouden, Johannes C.   +5 more
openaire   +4 more sources

Novel filagrinol-containing emollient

Vestnik dermatologii i venerologii, 2022
Background. In the last decade, there has been a significant increase in interest in the study of the role of epidermal barrier structural integrity in order to determine the prospects for its pathogenetic correction. It is now known that patients with filaggrin gene mutations have increased risk of developing atopic dermatitis, xerosis, ichthyosis ...
Elena S. Snarskaya, Anna V. Bratkovskaya
openaire   +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source

A Novel, Multifunctional, Natural-Based Emollient: An Exhaustive Characterization of Sharofeel DS

Cosmetics
Emollients are multifunctional, water-insoluble ingredients used in cosmetic products. This study aims to define the chemical and physical characteristics and test the activities of a new ester-based emollient, Sharofeel DS (DS), in comparison with other
Francesco Puzzo, Melania Di Liberto, Gabriele Valente, Roberta Maria Donadelli, Giangiacomo Beretta, Fabrizio Gelmini   +5 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source