Results 51 to 60 of about 34,989 (298)

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

Advanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu, Jun‐Han Zhang, Zhi‐Xuan Tan, Wei‐Bing Yan, Ya‐Ru Yuan, Yao Liu, Bing‐Di Wei, Meng‐Qi Ding, Zhuo‐Min Fu, Ying Liu, An‐Qi Wang, Lin Ma, Yong‐Hong Li, Er‐Qing Chai, Chao‐Jun Wei   +14 more
wiley   +1 more source

Prevalence and correlates of emotion dysregulation among children and adolescents in Lebanon: results from a National Survey

BMC Psychiatry
Background Data on Emotion Dysregulation among youth in Lebanon is scarce. Given that Emotion Dysregulation is associated with psychopathology and has a negative impact on youth outcomes, there is a need to better understand the prevalence, clinical and ...
Evelyne Baroud, Loay Alrojolah, Wael Shamseddeen, Lilian A. Ghandour, Martine Elbejjani, Marc Barakat, Leyla Akoury Dirani, Fadi T. Maalouf   +7 more
doaj   +1 more source

Unveiling the Role of Emotion Regulation in the Relationship between Intimate Partner Violence Increases and Post-Traumatic Stress Disorder: A Mediation Analysis

Behavioral Sciences
(1) Background: Experiencing intimate partner violence (IPV) can greatly impact victims’ physical and mental health, often leading to post-traumatic stress disorder (PTSD).
Federica Taccini, Alessandro Alberto Rossi, Stefania Mannarini   +2 more
doaj   +1 more source

Does trait mindfulness mediate the relationship between borderline personality symptoms and emotion dysregulation?

Borderline Personality Disorder and Emotion Dysregulation, 2023
Background Emotion dysregulation is core to many biopsychosocial models of Borderline Personality Disorder (BPD) and is often targeted as part of their associated psychological therapies.
Alison Roberts, Richard de Visser, Claire Rosten, Helen Startup, Clara Strauss   +4 more
doaj   +1 more source

Paternal Caffeine Exposure Programs Offspring Stress Vulnerability via Sperm Dlk1‐Dio3 Imprinting‐Directed Remodeling of a Novel Neural Circuit

Advanced Science, EarlyView.
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu, Gaole Dai, Sen Zhu, Shuai Zhang, Tingting Wang, Yuan Meng, Fang Yang, Xiaoyi Han, Hui Wang, Hao Kou, Dan Xu   +10 more
wiley   +1 more source

Emotion dysregulation and loneliness as predictors of food addiction

, 2019
Introduction: This study aimed to investigate whether multiple aspects of emotion dysregulation contribute to the etiology of Food Addiction (FA); as well as to provide further evidence and clarity regarding the role of loneliness on the development of ...
Alistar Turvill, Regina Holler, Tatsi, Eirini, Kamal, Atiya, Regina, Holler, Turvill, Alistair, Holler, Regina, Eirini Tatsi, Atiya Kamal   +8 more
core   +1 more source

Pharmacological Inhibition of FKBP51 Mitigates Early Life Adversity‐Induced Social Deficits in Male Mice

Advanced Science, EarlyView.
Early life adversity triggers persistent social subordination and brain‐wide molecular dysregulation. Pharmacological inhibition of the stress‐mediator FKBP51 during the adversity period prevents these long‐term deficits and restores normative social hierarchy.
Joeri Bordes, Xiuqi Ji, Serena Gasperoni, Choham Sudre‐Chinsky, Amirali Kalbasi, Daniela Harbich, Cornelia Flachskamm, Paula Fontanet, Sowmya Narayan, Manfred Uhr, Christian Namendorf, Camilla Bellone, Alon Chen, Felix Hausch, Juan Pablo Lopez, Mathias V. Schmidt   +15 more
wiley   +1 more source

Investigating the role of dimensions of UPPS-P model of impulsivity and age increasing in men’s emotion dysregulation [PDF]

فصلنامه علمی- پژوهشی اصول بهداشت روانی, 2018
Introduction: Given the importance of identifying factors influencing emotion dysregulation in order to design interventions to promotion emotion regulation in different age groups, present study aimed to investigating the role of dimensions of UPPS-P ...
Hashem Jebraeili, Alireza Moradi, Mojtaba Habibi   +2 more
doaj   +1 more source

Confabulation: Developing the ‘emotion dysregulation’ hypothesis [PDF]

Cortex, 2017
Confabulations offer unique opportunities for establishing the neurobiological basis of delusional thinking. As regards causal factors, a review of the confabulation literature suggests that neither amnesia nor executive impairment can be the sole (or perhaps even the primary) cause of all delusional beliefs - though they may act in concert with other ...
Oliver H, Turnbull, Christian E, Salas
openaire   +2 more sources

Streamlining Diagnosis of Bardet–Biedl Syndrome: New Diagnostic Algorithm With Updated Criteria

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Considerable advances have been made in our understanding of Bardet–Biedl syndrome (BBS), particularly in its core clinical features and molecular genetics, warranting an update to the existing diagnostic criteria framework. Using a rigorous, evidence‐based, and consensus‐driven process, a multidisciplinary group of international experts and ...
Jeremy J. Pomeroy, Jesse Richards, Brooke R. Sweeney, Seema Kumar, Katie E. Queen, Joshua Zaritsky, Carl H. Cramer, Elias I. Traboulsi, Brittni A. Scruggs, Erica E. Davis, Ekaterina Keifer, Emma McGibbon, Timothy Ogden, Bendert De Graaf, Tonia Hymers, Elizabeth Forsythe, Philip Beales   +16 more
wiley   +1 more source