Results 71 to 80 of about 467,385 (295)

Roles for Alexithymia, Emotion Dysregulation and Personality Features in Gambling Disorder: A Network Analysis [PDF]

, 2022
Although there is a growing interest in exploring the specific role of both emotional regulation processes and alexithymia in gambling disorder (GD), evidence remains scarce.
Potenza, Marc N., Mestre-Bach, Gemma, Jiménez-Murcia, Susana, Fernández-Aranda, Fernando, Susana Jiménez-Murcia, Gemma Mestre-Bach, Fernández Aranda, Fernando, Marc N. Potenza, Roser Granero, Granero, Roser, Fernando Fernández-Aranda, Jiménez Murcia, Susana   +11 more
core   +1 more source

PBRM1 Deficiency in Microglia Leads to Excessive Neurogenesis and Autism‐Like Behaviors via the CCL5‐CCR1/5‐β‐catenin Signaling Axis

Advanced Science, EarlyView.
Microglial PBRM1 deficiency drives excessive hippocampal neurogenesis by enhancing CCL5–CCR1/5 signaling, leading to autism‐like behaviors. A pro‐inflammatory IL1α+/TNFα+ microglial subset is identified as a key cellular contributor to this process. PBRM1 represses Ccl5 expression at the transcriptional level.
Yang‐Yang Duan, Lin‐Fei Jiao, Pei‐Pei Liu, Chun‐Hui Duan, Xiao Li, Zi‐Han Zhang, Yue‐Qi Zhang, Xin‐Li Ouyang, Hong‐Zhen Du, Sha Liu, Yi Tang, Zhao‐Qian Teng, Chang‐Mei Liu   +12 more
wiley   +1 more source

Does perceived emotional invalidation moderate the link between specific types of childhood traumas and emotion dysregulation in predicting psychological distress?

Acta Psychologica
Although emotion dysregulation has been established as a mediator between childhood traumas (CTs) and psychological distress, there is limited knowledge about the moderating role of perceived emotional invalidation (PEI) in the relationship between ...
Mehdi Rezaei, Zahra Paripishbar, Samaneh Khazaei   +2 more
doaj   +1 more source

Fronto-limbic neural variability as a transdiagnostic correlate of emotion dysregulation

Translational Psychiatry, 2021
Emotion dysregulation is central to the development and maintenance of psychopathology, and is common across many psychiatric disorders. Neurobiological models of emotion dysregulation involve the fronto-limbic brain network, including in particular the ...
Valeria Kebets, Pauline Favre, Josselin Houenou, Mircea Polosan, Nader Perroud, Jean-Michel Aubry, Dimitri Van De Ville, Camille Piguet   +7 more
doaj   +1 more source

A Hypothalamic Oxytocinergic–Sympathetic Axis Couples Anxiety Dysregulation With Impaired Tendon–Bone Repair

Advanced Science, EarlyView.
RCI is associated with functional suppression of oxytocinergic neurons in the PVN. Reduced PVNOXT neuronal activity contributes to altered sympathetic regulation involving the IML–sympathetic chain pathway, accompanied by changes in norepinephrine signaling at the BTI.
Liyang Wan, Tingmo Huang, Liyue Zeng, Ruixue Du, Hengshuo Zhang, Shen Liu, Tao Zhang, Jianzhong Hu, Hongbin Lu   +8 more
wiley   +1 more source

Emotion dysregulation as mediator between mentalizing capacity and affective states: An exploratory study

PCN Reports, 2023
Aim We intended to elucidate the relationship between mentalizing capacity and affective states by investigating the mediatory role of emotion dysregulation.
Saeed Ghanbari, Ahmad Asgarizadeh, Elahe Vahidi, Parisa Sadat Seyed Mousavi, Maryam Omidghaemi   +4 more
doaj   +1 more source

The Oxford Handbook of Emotion Dysregulation

, 2018
Emotion dysregulation—which is often defined as the inability to modulate strong affective states including impulsivity, anger, fear, sadness, and anxiety—is observed in nearly all psychiatric disorders.

core   +1 more source

CausalCellInfer: Prioritizing Cell‐Type‐Specific Disease Associations From Genetically Predicted Transcriptomes in Biobank Cohorts

Advanced Science, EarlyView.
Bulk and genotype‐imputed transcriptomes obscure the cellular drivers of complex disease. CausalCellInfer resolves them by integrating invariant marker selection, deep learning deconvolution, and regularized matrix completion. Applied to ∼500 000 UK Biobank participants across 29 traits, it uncovers hallmark cell‐type proportion shifts, including ...
Liangying Yin, Yujia Shi, Ruoyu Zhang, Yong Xiang, Jinghong Qiu, Pak‐Chung Sham, Hon‐Cheong So   +6 more
wiley   +1 more source

Emotion Dysregulation in the Structure of Self-Injurious Behavior

Консультативная психология и психотерапия, 2018
We present the results of the research of the link between emotion regulation and self-injurious behavior. The sample consisted of 706 respondents aged 14—35 (467 female).
Polskaya N.A.
doaj   +1 more source

Sub‐Second Ratiometric Fluorescence Imaging of Histamine Dynamics in Living Cells via a Supramolecular Probe

Advanced Science, EarlyView.
A tailored tripartite supramolecular ratiometric probe, engineered by modulating the fluorogenic guest's cationic locus, enables ultrafast histamine monitoring in living cells. Utilizing a competitive displacement mechanism, this system achieves a sub‐second response time with high selectivity.
Chenming Chan, Yujie Han, Yu‐Fei Song, Chunlei Jiang, Qi‐Wei Zhang   +4 more
wiley   +1 more source