Results 111 to 120 of about 495,179 (330)

Sleep disturbances in the prodromal phase of mood episodes in patients with bipolar disorder: a replicated single-case design

Journal for Person-Oriented Research
This study aims to examine whether objectively measured sleep disturbances occur in the prodromal phase of mood episodes in patients with bipolar disorder.
Stefan Knapen, Evelien Snippe, Arnout C. Smit, Robert A. Schoevers, Rixt F. Riemersma-van der Lek   +4 more
doaj   +1 more source

Effects of a brief mindfulness-based intervention on emotional regulation and levels of mindfulness in senior students [PDF]

, 2018
Mindfulness-based interventions have been applied in diverse populations and achieved mental health benefits. This study examined the effects of a brief mindfulness program for emotional regulation and levels of mindfulness on senior students in Brazil ...
A Chiesa, AC Ruocco, AC Silveira, AM Hayes, BW Smith, C Crane, EN Shearin, EZ Tourinho, F Zeidan, HC Schouwenburg, Ilana Andretta, J Carmody, J Coutinho, J Kabat-Zinn, J Kabat-Zinn, J Kabat-Zinn, J Pallant, J Slutsky, JD Creswell, JG Milsted, JM May, JM Singer, JMG Williams, JW Creswell, KL Gratz, KW Brown, L Cardaciotto, L Hawley, L Roemer, L Roemer, LC Vettese, Luana T. N. Mello, M Erogul, M Williams, MDS Costa, MMA Gama, MP Bardagi, P Robinson, PR Goldin, R Teper, RA Baer, RH Sampieri, Roberto Chiodelli, Saul N. Jesus, SC Hayes, SL Shapiro, SM Callegari-Jacques, SM Kosslyn, Statistical Package Social Sciences [SPSS], T Perich, Z Segal   +50 more
core   +2 more sources

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

The Geometry of Layer 2/3 Cortical Sound Processing in Slow Wave Sleep

Advanced Science, EarlyView.
Sleep is associated with a sensory disconnection whose mechanisms remain elusive. Large neuronal population recordings in the auditory cortex revealed that, in NREM sleep, the neural code for sounds is highly similar to wakefulness, but coordinated modulations of neuron responsiveness intermittently disconnect the local cortical networks from sensory ...
Allan Muller, Anton Filipchuk, Sophie Bagur, Brice Bathellier   +3 more
wiley   +1 more source

Early Behavioral Inhibition and Emotion Regulation: Pathways Toward Social Competence in Middle Childhood [PDF]

, 2015
Elizabeth C. Penela, Olga L. Walker, Kathryn A. Degnan, Nathan A. Fox, Heather A. Henderson   +4 more
openalex   +1 more source

Interpersonal emotion regulation: a review of social and developmental components [PDF]

, 2018
A staple theme in clinical psychology, emotion regulation, or the ability to manage one's emotions, is directly linked with personal wellbeing and the ability to effectively navigate the social world.
Barthel, Abigail L., Doan, Stacey N., Hay, Aleena, Hofmann, Stefan G.   +3 more
core   +1 more source

Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors

Advanced Science, EarlyView.
Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen, Riya Gupta, Yosuke M. Morizawa, Yu Qin, Xingyu Du, Cynthia Pang, Osama Al‐Dalahmah, Maura B. Dupont, Guang Yang   +8 more
wiley   +1 more source

Can we identify emotion over-regulation in infancy? Associations with avoidant attachment, dyadic emotional interaction and temperament [PDF]

, 2012
Emotion over-regulation in infancy has seldom been the focus of empirical research. This study analysed the specificities of overregulation when compared with under-regulation (maladaptive) and adaptive regulation by testing its association with ...
Ainsworth, Aldao, Bates, Beebe, Biringen, Braungart, Braungart-Rieker, Calkins, Calkins, Campos, Cassidy, Cicchetti, Cole, Cole, Corriveau, Crugnola, DeGangi, Diamond, Diener, Dillon, Eisenberg, Feldman, Flanders, Goldberg, Graffar, Graziano, Graziano, Gross, Keenan, Kopp, Koulomzin, MacKenzie, Main, Maughan, Meins, Mikulincer, Miller, Morris, Newland, NICHD Early Child Care Research Network, Rothbart, Schore, Srivastava, Sroufe, Sroufe, Thompson, Vaughn, Volling   +47 more
core   +3 more sources

XIAP Stabilizes DDRGK1 to Promote ER‐Phagy and Protects Against Noise‐Induced Hearing Loss

Advanced Science, EarlyView.
Mechanism of GAS‐mediated protection against noise‐induced hearing loss (NIHL). Noise exposure activates the ATF4/eIF2α axis, downregulating XIAP and promoting DDRGK1 degradation, thereby inhibiting ER‐phagy and leading to hair cell (HC) death. GAS treatment rescues XIAP and DDRGK1 expression, reactivating ER‐phagy to mitigate HC loss, synaptic damage,
Lin Yan, Yuhua Zhang, Jiawei Du, Yongjun Zhu, Wei Cao, Yongjie Wei, Han Wu, Shiyu Qiu, Shiyi Pan, Lian Chen, Pingping Liang, Renjie Chai, Jianming Yang, Qiaojun Fang   +13 more
wiley   +1 more source

Help-seeking behaviors among Chinese people with mental disorders: a cross-sectional study

BMC Psychiatry, 2019
Background Failure to seek treatment for mental health disorders is a serious public health concern. Unfortunately, there is little insight into help-seeking and its associated factors in China which has undergone rapid economic development in the past ...
Huifang Yin, Klaas J. Wardenaar, Guangming Xu, Hongjun Tian, Robert A. Schoevers   +4 more
doaj   +1 more source