Results 111 to 120 of about 2,616,516 (303)

Making Sweat Measurable: Induction, Sampling, and Refreshment in Wearable Biofluid Sensing

Advanced Science, EarlyView.
Wearable sweat sensing relies not only on chemical detection but also on controlled biofluid management. This Review integrates sweat physiology, induction strategies, and microfluidic sampling architectures, demonstrating how flux, transport, and refreshment shape measurement reliability.
Soyoung Shin, Wei Gao
wiley   +1 more source

VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis

Advanced Science, EarlyView.
Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang, Bing‐Jie Tang, Jia‐Yi Li, Shu‐Lan Xie, Shumin Duan, Junping Chen, Shengmei Zhu, Zhen‐Zhong Xu   +7 more
wiley   +1 more source

Disentangling comorbidity: symptom dimensions of internalizing and functional disorders in a large general population sample

BMC Psychiatry
Background Internalizing disorders (IDs) and functional disorders (FDs) are highly comorbid, however the mechanisms underlying their co-occurrence remain unclear.
Urvi Saini, Steven H. Aggen, Albertine J. Oldehinkel, Judith G. M. Rosmalen, Hanna M. van Loo   +4 more
doaj   +1 more source

Targeting CXCR2 in Nociceptive Sensory Neurons Offers Novel Therapeutic Potentials for Postoperative Pain

Advanced Science, EarlyView.
Tissue incision induces CXCL5 release, which activates neuronal CXCR2 on incision‐innervating sensory neurons. Neuronal CXCR2 couples with TRPA1 to drive mechanical pain and engages p38 MAPK signaling to upregulate TRPV1 and promote heat pain. Targeted Cxcr2 knockdown relieves incisional pain while preserving CXCR2‐dependent neutrophil responses ...
Yushuang Pan, Peiyi Li, Yufeng Chen, Zishan Dong, Yuanyuan Li, Boyu Liu, Yan Tai, Chuan Wang, Jianqiao Fang, Chengyu Yin, Boyi Liu   +10 more
wiley   +1 more source

A qualitative study exploring early experiences of misophonia through firsthand perspectives

Frontiers in Psychiatry
IntroductionMisophonia is characterized by highly aversive affective, physiological, and behavioral responses to specific auditory and related cues. Although research on misophonia has increased in recent years, relatively little is known about onset ...
Emily C. Gates, Alyssa Gabbidon, Grace A. Heppes, M. Zachary Rosenthal, M. Zachary Rosenthal   +4 more
doaj   +1 more source

Single‐Cell Profiling Reveals a Protective WNT5A‐ATF3‐FOSB Signaling Axis in Hair Follicle Stem Cells During Androgenetic Alopecia

Advanced Science, EarlyView.
Androgenetic alopecia (AGA) is a common form of hair loss with limited treatment options. Silencing of WNT5A signaling, which is widely known as the trigger of the ncWNT signaling pathway, happens in hair follicle stem cells from balding areas. It leads to downregulation of ATF3 and its target FOSB.
Ruiyu Luo, Ke Fang, Changjiang Zhao, Jiachao Xiong, Yuan Zhu, Mingyang Lu, He Yan, Zihan Li, Baojin Wu, Hua Jiang, Yufei Li   +10 more
wiley   +1 more source

The Effect of the Emotion Regulation Education Program on the Emotion Regulation Skills of the Children Staying in the Children’s Houses Site

The study aimed to examine the effect of the Emotion Regulation Training Program on the emotion regulation skills of children residing in children’s homes and to ascertain the opinions of the institution’s child development specialist and care staff ...
ŞEPİTÇİ SARIBAŞ, MERVE, Merve ŞEPİTCİ SARIBAŞ, Fatma TEZEL ŞAHİN, TEZEL ŞAHİN, FATMA   +3 more
core   +1 more source

Fear of emotion in adolescents: the Modified Affective Control Scale for Adolescents-Revised [PDF]

, 2010
Difficulties in emotion regulation, in the form of fear of emotion, have been studied in adults but have received scant attention within the adolescent population.
Koh, Delphine
core  

Dual‐Organelle Secretome Conjugation and Organ‐Uptake Tracking (DuO‐SCOUT) Enables Deep and Sensitive Mapping of the Secreted Proteins

Advanced Science, EarlyView.
A novel dual‐organelle proximity labeling platform, DuO‐SCOUT, decodes the complex landscape of systemic organ‐organ communication by capturing both classical and unconventional secretomes. Application in metabolic models maps the adipose‐to‐brain secretory relay, identifying selective extra‐hypothalamic sites for adipose‐derived factors and expanding ...
Fenglian Yang, Rui Qian, Jiaxing Song, Xingqi Meng, Jin Young Kim, Kwok On Lai, Li Wang, Liang Zhang   +7 more
wiley   +1 more source

Help-seeking behaviors among Chinese people with mental disorders: a cross-sectional study

BMC Psychiatry, 2019
Background Failure to seek treatment for mental health disorders is a serious public health concern. Unfortunately, there is little insight into help-seeking and its associated factors in China which has undergone rapid economic development in the past ...
Huifang Yin, Klaas J. Wardenaar, Guangming Xu, Hongjun Tian, Robert A. Schoevers   +4 more
doaj   +1 more source