XIAP Stabilizes DDRGK1 to Promote ER‐Phagy and Protects Against Noise‐Induced Hearing Loss
Advanced Science, EarlyView.Mechanism of GAS‐mediated protection against noise‐induced hearing loss (NIHL). Noise exposure activates the ATF4/eIF2α axis, downregulating XIAP and promoting DDRGK1 degradation, thereby inhibiting ER‐phagy and leading to hair cell (HC) death. GAS treatment rescues XIAP and DDRGK1 expression, reactivating ER‐phagy to mitigate HC loss, synaptic damage,
Lin Yan +13 more
wiley +1 more source
Burnout Syndrome and Emotional Labor in Leaders and Subordinates: A Dyad Analysis
Social SciencesBurnout Syndrome is considered a chronic response to occupational stressors in the work environment. Social interactions constitute one of the stressors at work that can generate negative feelings that trigger a process of contagion of the syndrome among
Michelle Engers Taube +3 more
doaj +1 more source
Job-related stress and burnout [PDF]
, 2002 Occupational stress is a topic of substantial interest to organizational researchers and managers, as well as society at large. Stress arising from work conditions can be pervasive and significant in its impact on individuals, their families and ...
Cooper, Cary L. +1 more
core +1 more source
Advanced Science, EarlyView.Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao +36 more
wiley +1 more source
Emotional demands and entrepreneurial burnout: the role of autonomy and job satisfaction. [PDF]
Small Bus Econ (Dordr), 2022 Tahar YB +5 more
europepmc +1 more source
A Wearable Brain–Computer Interface for Mitigating Car Sickness via Attention Shifting
Advanced Science, EarlyView.Car sickness poses a major challenge in vehicular travel, yet effective nonpharmacological solutions are scarce. We developed a wearable, closed‐loop mindfulness BCI that uses real‐time EEG‐based neurofeedback to shift attention away from motion‐induced discomfort. Validated in real‐car experiments involving >100$>100$ susceptible individuals, over 83%
Jiawei Zhu +14 more
wiley +1 more source
Leaders' mental health in times of crisis: work intensification, emotional demands and the moderating role of organizational support and self-efficacy. [PDF]
Front Psychol, 2023 Wittmers A, Maier GW.
europepmc +1 more source
Solidarity across generations in New Zealand: Factors influencing parental support for children within a three-generational context [PDF]
, 2004 Interest in ascertaining the nature and extent of intergenerational exchanges between those in mid-life, and members of their kinship network has arisen because demographic, social and policy changes have brought into question the ability of individuals ...
Dharmalingam, Arunachalam +1 more
core +1 more source
Recent Advances in Decoupling Strategies for Soft Sensors
Advanced Science, EarlyView.This review provides an overview of recent advances in decoupling strategies for soft sensors. It summarizes single‐modal sensors that are insensitive to stretching, bending, crosstalk, and other environmental interferences, and highlights emerging multimodal decoupling methods enabled by spatiotemporal information and machine learning.
Yangbo Yuan +4 more
wiley +1 more source
Emotional demands and all-cause and diagnosis-specific long-term sickness absence: a prospective cohort study in Sweden. [PDF]
Eur J Public Health, 2023 Framke E +6 more
europepmc +1 more source