Results 111 to 120 of about 3,365,275 (312)

VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis

open access: yesAdvanced Science, EarlyView.
Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang   +7 more
wiley   +1 more source

Building young children’s emotional competence and self- regulation from birth : the begin to... ECSEL approach [PDF]

open access: yes, 2018
Neuroscientific advances and child development studies show 0-6 years represents a sensitive period for the development of emotional competence—the ability to identify, understand, express and regulate emotion, all foundational to self-regulation ...
Denham, Susanne A.   +5 more
core   +1 more source

Targeting CXCR2 in Nociceptive Sensory Neurons Offers Novel Therapeutic Potentials for Postoperative Pain

open access: yesAdvanced Science, EarlyView.
Tissue incision induces CXCL5 release, which activates neuronal CXCR2 on incision‐innervating sensory neurons. Neuronal CXCR2 couples with TRPA1 to drive mechanical pain and engages p38 MAPK signaling to upregulate TRPV1 and promote heat pain. Targeted Cxcr2 knockdown relieves incisional pain while preserving CXCR2‐dependent neutrophil responses ...
Yushuang Pan   +10 more
wiley   +1 more source

Emotional regulation and Arnold’s self-ideal: a way to flourishment

open access: yesFrontiers in Psychology
The convergence of researchers in the fields of flourishing, moral psychology, and social–emotional studies has reached a stage where developing a theory that connects emotional regulation and flourishing is meaningful.
Fátima Ruiz-Fuster   +2 more
doaj   +1 more source

Single‐Cell Profiling Reveals a Protective WNT5A‐ATF3‐FOSB Signaling Axis in Hair Follicle Stem Cells During Androgenetic Alopecia

open access: yesAdvanced Science, EarlyView.
Androgenetic alopecia (AGA) is a common form of hair loss with limited treatment options. Silencing of WNT5A signaling, which is widely known as the trigger of the ncWNT signaling pathway, happens in hair follicle stem cells from balding areas. It leads to downregulation of ATF3 and its target FOSB.
Ruiyu Luo   +10 more
wiley   +1 more source

EMOTIONAL INTELLIGENCE MODEL FOR DIRECTORS OF RESEARCH CENTERS IN MEXICO [PDF]

open access: yes
The objective of this article is to show the results of IE-Martruj, a model designed for measuring emotional intelligence in directors of research centers (RCs), which was appliedto forty-three directors of research centers in Mexico.
LUIS ARTURO RIVAS TOVAR   +1 more
core  

Dual‐Organelle Secretome Conjugation and Organ‐Uptake Tracking (DuO‐SCOUT) Enables Deep and Sensitive Mapping of the Secreted Proteins

open access: yesAdvanced Science, EarlyView.
A novel dual‐organelle proximity labeling platform, DuO‐SCOUT, decodes the complex landscape of systemic organ‐organ communication by capturing both classical and unconventional secretomes. Application in metabolic models maps the adipose‐to‐brain secretory relay, identifying selective extra‐hypothalamic sites for adipose‐derived factors and expanding ...
Fenglian Yang   +7 more
wiley   +1 more source

The Effect of Emotional Labor on Young Nurses' Job Burnout: The Mediating Role of Social Support and Emotional Regulation

open access: yesNursing Open
Aim To evaluate the impact of emotional labor on job burnout among young nurses and investigate the mediating roles of social support and emotional regulation. Design A cross‐sectional survey. Methods The cross‐sectional study recruited 1103 young nurses
Yixin Luo   +5 more
doaj   +1 more source

Relating emotional intelligence to academic achievement among university students in Barbados [PDF]

open access: yes, 2012
This study investigated the relationships between emotional intelligence and academic achievement among 151 undergraduate psychology students at The University of the West Indies (UWI), Barbados, making use of Barchard (2001)'s Emotional Intelligence ...
Grace A. Fayombo, Fayombo, Grace A.
core   +1 more source

Home - About - Disclaimer - Privacy