Results 11 to 20 of about 70 (67)
Cutaneous Rosai‐Dorfman Disease With MAP2K1 Mutation Treated With Encorafenib and Binimetinib
JEADV Clinical Practice, EarlyView.ABSTRACT Rosai‐Dorfman disease (RDD) is a rare histiocytic disorder with unifocal to multisystemic involvement. Activating mutations in the MAPK/ERK pathway can occur in up to 50% of RDD cases. We report a case of cutaneous RDD (C‐RDD) with facial and truncal lesions harboring an activating MAP2K1 (MEK1) mutation that showed a complete response to a ...
Melike Ak +2 more
wiley +1 more source
Histopathology, EarlyView.New concepts, innovations and some issues have emerged since the adoption a decade ago of WHO/ISUP grading for CCRCC and PRCC. Continued use of the WHO/ISUP grading for CCRCC and PRCC has been upheld by newer studies, and practice guidance for some of the grading issues, where data are available, is provided.
Gladell P. Paner +4 more
wiley +1 more source
Cytologic Characteristics of the Feline Ovary at Different Sexual Stages
Veterinary Clinical Pathology, EarlyView.ABSTRACT Background Cytology is a valuable diagnostic tool in veterinary medicine, allowing rapid and minimally invasive diagnosis. However, its application in the reproductive tracts of small animals is limited, primarily used to assess mammary masses and stage the estrous cycle.
Alba Martí +4 more
wiley +1 more source
Histiocytosis development and clinical variation through the lens of genomics
The Journal of Pathology, Volume 270, Issue 1, Page 23-39, September 2026.Abstract Histiocytic neoplasms are rare haematologic diseases characterised by clonal expansions of cells with a monocyte, macrophage or dendritic cell phenotype. Their clinical manifestations are diverse, ranging from indolent lesions to aggressive systemic disease.
Paul G Kemps +3 more
wiley +1 more source
Clinical Case Reports, Volume 14, Issue 8, August 2026.ABSTRACT H syndrome is a rare autosomal recessive disorder caused by mutations in the SLC29A3 gene. We report three pediatric patients with a homozygous c.1309G>A (p.Gly437Arg) mutation presenting with distinct phenotypic variations. These cases expand the clinical spectrum and emphasize the importance of early genetic diagnosis and family counseling.
Mohammad Najajrah +5 more
wiley +1 more source
Primary Tracheal Rosai‐Dorfman Disease Coexisting With Active Pulmonary Tuberculosis
Respirology Case Reports, Volume 14, Issue 8, August 2026.We report a rare case of primary tracheal Rosai‐Dorfman disease (RDD) with active pulmonary tuberculosis. Bronchoscopic resection immediately relieved > 90% airway obstruction, and anti‐tuberculosis therapy was given, resulting in no recurrence at one‐year follow‐up. ABSTRACT Rosai‐Dorfman disease (RDD) rarely involves the trachea, and active pulmonary
Shijie Yang +4 more
wiley +1 more source
A Recurrent Indurated Plaque on the Thigh
JEADV Clinical Practice, EarlyView.
Tram T. Tran +3 more
wiley +1 more source
Chronic Pruritic Papular Eruption in an Elderly Man
JEADV Clinical Practice, EarlyView.
Filipe Monteiro +6 more
wiley +1 more source
Clinical Case Reports, Volume 14, Issue 5, May 2026.ABSTRACT Autoimmune hepatitis (AIH) following COVID‐19 vaccination is a rare adverse event. We present the case of a 55‐year‐old male with a history of ulcerative colitis (UC) who developed AIH 3 weeks after receiving his second dose of the Pfizer–BioNTech mRNA vaccine. He presented with jaundice and significantly elevated liver enzymes. A liver biopsy
Marwah Algodi +6 more
wiley +1 more source
Clinical Case Reports, Volume 14, Issue 4, April 2026.ABSTRACT Rosai‐Dorfman disease is a rare non‐Langerhans cell histiocytic disorder. It is common in male children and young adults of African descent. It is classified into sporadic and familial types. The most common clinical presentation is massive bilateral cervical lymphadenopathy associated with constitutional symptoms. Histiocytic emperipolesis is
George Evele +2 more
wiley +1 more source