Results 31 to 40 of about 8,573,374 (325)

Non-empirical pairing functional

, 2007
The present contribution reports the first systematic finite-nucleus calculations performed using the Energy Density Functional method and a non-empirical pairing functional derived from low-momentum interactions.
Duguet, T., Lesinski, T.
core   +3 more sources

Drug*placebo interaction effect may bias clinical trials interpretation: hybrid balanced placebo and randomized placebo-controlled design

BMC Medical Research Methodology, 2016
Background Conventional randomized placebo-controlled study design assumes the absence of drug*placebo interaction. We hypothesized the presence of such an interaction and that conventionally estimated drug effect might be biased.
Muhammad M. Hammami, Safa Hammami, Reem Al-Swayeh, Eman Al-Gaai, Faduma Abdi Farah, Sophia J. S. De Padua   +5 more
doaj   +1 more source

A more principled use of the p-value? Not so fast: a critique of Colquhoun’s argument [PDF]

Royal Society Open Science, 2019
The usefulness of the statistic known as the p-value, as a means of quantifying the strength of evidence for the presence of an effect from empirical data has long been questioned in the statistical community.
Ognjen Arandjelović
doaj   +1 more source

Constructive quantization: approximation by empirical measures [PDF]

, 2011
In this article, we study the approximation of a probability measure $\mu$ on $\mathbb{R}^{d}$ by its empirical measure $\hat{\mu}_{N}$ interpreted as a random quantization. As error criterion we consider an averaged $p$-th moment Wasserstein metric.
Dereich, Steffen, Scheutzow, Michael, Schottstedt, Reik   +2 more
core   +3 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Semi-empirical model of MOST and passive devices focused on narrowband RF blocks [PDF]

, 2012
This paper presents a semi-empirical modeling of MOST and passive elements to be used in narrowband radiofrequency blocks for nanometer technologies. This model is based on a small set of look-up tables (LUTs) obtained via electrical simulations.
Fiorelli, Rafaella, Peralías Macías, Eduardo, Rueda Rueda, Adoración, Silveira Noguerol, Fernando   +3 more
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Intonation and timing in singing early music is unrelated to respiration synchronization

Scientific Reports
Musical ensemble performance offers a unique context for investigating complex interpersonal coordination. Hyperscanning research revealed the synchronization of physiological processes during coordinated musical interaction.
Anton Schreiber, Klaus Frieler, Elke B. Lange   +2 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Timbral effects on consonance disentangle psychoacoustic mechanisms and suggest perceptual origins for musical scales

Nature Communications
The phenomenon of musical consonance is an essential feature in diverse musical styles. The traditional belief, supported by centuries of Western music theory and psychological studies, is that consonance derives from simple (harmonic) frequency ratios ...
Raja Marjieh, Peter M. C. Harrison, Harin Lee, Fotini Deligiannaki, Nori Jacoby   +4 more
doaj   +1 more source