Results 61 to 70 of about 19,429 (283)

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Large deviation principles for empirical measures of colored random graphs

, 2010
For any finite colored graph we define the empirical neighborhood measure, which counts the number of vertices of a given color connected to a given number of vertices of each color, and the empirical pair measure, which counts the number of edges ...
Doku-Amponsah, Kwabena, Mörters, Peter
core   +1 more source

Information entropy as a measure of the quality of a nuclear density distribution [PDF]

, 1997
The information entropy of a nuclear density distribution is calculated for a number of nuclei. Various phenomenological models for the density distribution using different geometry are employed.
Antonov A. N., Atti C., Bialynicki-Birula I., C. P. Panos, Canosa N., Daskaloyannis C. B., G. A. Lalazissis, Gadre S. R., Gadre S. R., Gambhir Y. K., Gambhir Y. K., Ghosh S. K., Koga T., Lalazissis G. A., Lalazissis G. A., Ring P., S. E. Massen, S. S. Dimitrova, Stoitsov M. V.   +18 more
core   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Development of Automated Sleep Stage Classification System Using Multivariate Projection-Based Fixed Boundary Empirical Wavelet Transform and Entropy Features Extracted from Multichannel EEG Signals

Entropy, 2020
The categorization of sleep stages helps to diagnose different sleep-related ailments. In this paper, an entropy-based information–theoretic approach is introduced for the automated categorization of sleep stages using multi-channel electroencephalogram (
Rajesh Kumar Tripathy, Samit Kumar Ghosh, Pranjali Gajbhiye, U. Rajendra Acharya   +3 more
doaj   +1 more source

Improved Butterfly Optimizer-Configured Extreme Learning Machine for Fault Diagnosis

Complexity, 2021
An efficient intelligent fault diagnosis model was proposed in this paper to timely and accurately offer a dependable basis for identifying the rolling bearing condition in the actual production application.
Helong Yu, Kang Yuan, Wenshu Li, Nannan Zhao, Weibin Chen, Changcheng Huang, Huiling Chen, Mingjing Wang   +7 more
doaj   +1 more source

Empirical Risk Minimization With Relative Entropy Regularization

IEEE Transactions on Information Theory
The empirical risk minimization (ERM) problem with relative entropy regularization (ERM-RER) is investigated under the assumption that the reference measure is a $σ$-finite measure, and not necessarily a probability measure. Under this assumption, which leads to a generalization of the ERM-RER problem allowing a larger degree of flexibility for ...
Samir M. Perlaza, Gaetan Bisson, Iñaki Esnaola, Alain Jean-Marie, Stefano Rini   +4 more
openaire   +3 more sources

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Estimating Entropy of Data Streams Using Compressed Counting [PDF]

, 2009
The Shannon entropy is a widely used summary statistic, for example, network traffic measurement, anomaly detection, neural computations, spike trains, etc. This study focuses on estimating Shannon entropy of data streams.
Li, Ping
core  

Quantum information as a non-Kolmogorovian generalization of Shannon's theory [PDF]

, 2015
In this article we discuss the formal structure of a generalized information theory based on the extension of the probability calculus of Kolmogorov to a (possibly) non-commutative setting.
Bellomo, G., Bosyk, G. M., Holik, F.
core   +4 more sources