Results 31 to 40 of about 51,164,453 (245)
Assessing temporary product-specific subsidies: a time series intervention analysis
Research in StatisticsWe propose an analytical forecasting framework to quantify the distortionary effects of product-specific subsidies. The novelty consists of a dual approach combining intervention analysis and a state-space modeling approach to construct and assess ...
David Leuwer +2 more
doaj +1 more source
Behavioral Sciences, 2023 Many situations require coordinated actions of individuals to achieve common goals. Such situations include organizing mass protests or adjusting behavior to new behavioral recommendations that aim to slow down the spread of a contagious disease. However,
Thomas Neumann, Paul Bengart, Bodo Vogt
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Adopting Scrum in Hybrid Settings, in a University Course Project: Reflections and Recommendations
IEEE AccessAgile software development (ASD) methods such as Scrum promote collocated team collaboration. However, adopting Scrum in hybrid work environments can pose challenges.
Woubshet Behutiye +2 more
doaj +1 more source
Media and Communication, 2019 The intense use of digital media among children and adolescents raises concerns about online risks. In response, digital literacy frameworks for formal education usually include a set of protective skills.
Priscila Berger, Jens Wolling
doaj +1 more source
Personality traits and meat consumption: The mediating role of animal-related ethical concerns
Frontiers in Psychology, 2023 Prior research suggests that personality traits are associated with meat consumption. However, this association is not uniform across all types of meat.
Gonzalo Haefner +2 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Advancing genomics research in Ireland: Part Two. Irish Health Research Forum report and recommendations [PDF]
, 2021 This report presents the proceedings of the Irish Health Research Forum on 12th May 2021. This is the second report to focus on advancing genetics and genomics in Ireland, and makes key recommendations for health research policy and practice in ...
Health Research Charities Ireland
core +1 more source