Results 51 to 60 of about 4,856,660 (339)

A construction and empirical research of the journal disruption index based on open citation data [PDF]

, 2023
Yuyan Jiang, Xueli Liu
openalex   +1 more source

Research Findings on Empirical Evaluation of Requirements Specifications Approaches [PDF]

, 2009
Numerous software requirements specification (SRS) approaches have been proposed in software engineering. However, there has been little empirical evaluation of the use of these approaches in specific contexts.
Condori-Fernandez, Nelly, Daneva, Maya, Dieste, Oscar, Pastor, Oscar, Sikkel, Klaas, Wieringa, Roel   +5 more
core   +1 more source

Evaluating Judges and Judicial Institutions: Reorienting the Perspective [PDF]

, 2010
Empirical scholarship on judges, judging, and judicial institutions, a staple in political science, is becoming increasingly popular in law schools. We propose that this scholarship can be improved and enhanced by greater collaboration between empirical ...
Gulati, Mitu, Klein, David E., Levi, David F.   +2 more
core   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Economic development benefits or social inequality hinders? Intergenerational educational mobility in 49 countries

Humanities & Social Sciences Communications
This study employs global survey data and multilevel linear models to analyze the effects of contextual factors on intergenerational educational mobility across 49 countries.
Jiyue Li, Qian Zhang
doaj   +1 more source

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte, Lucy Norcliffe‐Kaufmann, Maria Luisa Cotrina, Zenith Khan, Kaia Dalamo, Patricio Millar Vernetti, Matthew Lawless, Elisabetta Morini, Monica Salani, Marla Weetall, Jana Narasimhan, Agostino G. Rocha, Susan A. Slaugenhaupt, Horacio Kaufmann   +13 more
wiley   +1 more source

Subjective Evaluation of Media Content as a Moderator of Media Effects on European Identity: Mere Exposure and the Hostile Media Phenomenon

Media and Communication, 2017
This paper posits that the concept of European identity is an important indicator of the legitimacy of the European Union (EU). It further assumes that the exposure to EU related media content can influence the feeling of European identity.
Waqas Ejaz, Marco Bräuer, Jens Wolling
doaj   +1 more source

Rethinking empirical research into Children in Care and Contact [PDF]

, 2016
Current literature in relation to contact for Children in Care reveals that there have been a number of theories that have informed the current notion of contact and these are underpinned by psychological and psychosocial assumptions about identity ...
Simpson, Jenny
core  

On the Stability of Research Joint Ventures: Implications for Collusion [PDF]

, 2008
Though there is a body of theoretical literature on research joint ventures (RJV) participation facilitating collusion, empirical tests are rare. Even more so, there are few empirical tests on the general theme of collusion.
Duso, Tomaso, Pennings, Enrico, Seldeslachts, Jo   +2 more
core   +3 more sources