Results 51 to 60 of about 51,164,453 (245)

The Relevance of Empirical Research in Bioethics [PDF]

Schizophrenia Bulletin, 2005
Empirical research related to ethical issues in clinical research has grown dramatically in recent years. However, little attention has been devoted to the ethical relevance of the findings from this research. In order to examine the value and limitations of ethics-related empirical research, we discuss 3 case studies involving research with stored ...
Franklin G, Miller, David, Wendler
openaire   +2 more sources

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Conducting Empirical Studies in Industry: Balancing Rigor and Relevance

, 2013
Empirical Software Engineering research has achieved considerable results in building our knowledge about selecting and applying appropriate empirical methods for technology evaluation.
Jain, Shilpi, Shilpi Jain, Babar, M., Jude Fernandez, Fernandez, Jude, Ali Babar, Muhammad, Jain, S., Fernandez, J., Muhammad Ali Babar   +8 more
core   +1 more source

Economic development benefits or social inequality hinders? Intergenerational educational mobility in 49 countries

Humanities & Social Sciences Communications
This study employs global survey data and multilevel linear models to analyze the effects of contextual factors on intergenerational educational mobility across 49 countries.
Jiyue Li, Qian Zhang
doaj   +1 more source

Evaluating GenAI‐produced feedback on undergraduate bioscience essays against good higher education feedback practice

FEBS Open Bio, EarlyView.
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court, Nigel Francis, Andrew Shore, Stephen Rutherford   +3 more
wiley   +1 more source

The European advantage in empirical comparative law

Published online: 09 January 2025Empirical legal studies in Europe lag behind developments in the US. By contrast, comparative law is a prominent field of research and teaching in many European countries, while it plays a more limited role in the US ...
SIEMS, Mathias
core   +1 more source

Hidden Empirical Research Ethics: A Review of Three Health Journals From 2005 Through 2006

, 2008
We hypothesized that a significant amount of empirical data pertinent to research ethics is currently inaccessible to research ethics committee or Institutional Review Board (IRB) members for at least three reasons: it is published in non-ethics journals;
Volpe, Rebecca L., DuBois, James M., Rangel, Erica K.   +2 more
core   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source