Results 41 to 50 of about 4,754,770 (321)

Internet sex addiction: a review of empirical research [PDF]

open access: yes, 2012
The advent of the internet has added another medium in which people can engage in sexual behaviour. This ranges from the passive consumption of online pornography to the interactive exchange of sexual content in cybersex chat rooms.
Griffiths, MD
core  

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Does Gallery Lighting Really Have an Impact on Appreciation of Art? An Ecologically Valid Study of Lighting Changes and the Assessment and Emotional Experience With Representational and Abstract Paintings

open access: yesFrontiers in Psychology, 2019
We report two studies considering the potential for gallery lighting conditions to modulate appraisals and emotional experience with works of visual art.
Matthew Pelowski   +5 more
doaj   +1 more source

Neural synchronization is strongest to the spectral flux of slow music and depends on familiarity and beat salience

open access: yeseLife, 2022
Neural activity in the auditory system synchronizes to sound rhythms, and brain–environment synchronization is thought to be fundamental to successful auditory perception. Sound rhythms are often operationalized in terms of the sound’s amplitude envelope.
Kristin Weineck   +2 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Preliminary Survey on Empirical Research Practices in Requirements Engineering [PDF]

open access: yes, 2012
Context and Motivation:\ud Based on published output in the premium RE conferences and journals, we observe a growing body of research using both quantitative and qualitative research methods to help understand which RE technique, process or tool work ...
Condori-Fernández, Nelly   +2 more
core   +2 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Online gaming addiction in children and adolescents: a review of empirical research [PDF]

open access: yes, 2012
Background and aims: Research suggests that excessive online gaming may lead to symptoms commonly experienced by substance addicts. Since games are particularly appealing to children and adolescents, these individuals may be more at risk than other ...
Griffiths, MD, Kuss, DJ
core   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

open access: yesFEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Rethinking empirical research into Children in Care and Contact [PDF]

open access: yes, 2016
Current literature in relation to contact for Children in Care reveals that there have been a number of theories that have informed the current notion of contact and these are underpinned by psychological and psychosocial assumptions about identity ...
Simpson, Jenny
core  

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