Results 31 to 40 of about 118,227 (339)
Looking for Design in Materials Design
, 2004 Despite great advances in computation, materials design is still science fiction. The construction of structure-property relations on the quantum scale will turn computational empiricism into true design.Comment: 3 pages, 1 ...
CS Smith +5 more
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Empiricism, Stances, And The Problem Of Voluntarism [PDF]
, 2011 Classical empiricism leads to notorious problems having to do with the (at least prima facie) lack of an acceptable empiricist justification of empiricism itself. Bas van Fraassen claims that his idea of the empirical stance can deal with such problems.
Baumann, Peter
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Two Faces of Transcendental Empiricism: Gilles Deleuze and John McDowell
RUDN Journal of PhilosophyThe research presents a comparative analysis of John McDowell’s and Gilles Deleuze’s conceptions of transcendental empiricism. The very name of this conception bears in itself a kind of paradox, since Kant (the father of transcendental philosophy ...
Danila A. Volkov, Maksim D. Evstigneev
doaj +1 more source
Au-delà de l’étiquette historiographique : l’empirisme singulier de J. N. Tetens
Astérion, 2018 Beyond the usual conception of Johann Nikolaus Tetens as the “German Locke”, this paper wants to reassess the distinctive German context of the empiricist reference in the Essay on the Reform of the Speculative Philosophy (1775) and in the Philosophical ...
David Wittmann
doaj +1 more source
There Is No Pure Empirical Reasoning [PDF]
, 2017 The justificatory force of empirical reasoning always depends upon the existence of some synthetic, a priori justification. The reasoner must begin with justified, substantive constraints on both the prior probability of the conclusion and certain ...
Ayer +44 more
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Ce qu’atteint l’expérience du vouloir : Hume, Locke, Malebranche
Astérion, 2016 Starting from an excerpt of An Enquiry Concerning Human Understanding (section 7, part I), this article compares the conceptions that Hume, Locke and Malebranche uphold regarding the experience we have of the power of our will.
Sophie Bergont
doaj +1 more source
Kant on empiricism and rationalism [PDF]
, 2013 This paper aims to correct some widely held misconceptions concerning Kant's role in the formation of a widespread narrative of early modern philosophy.
Vanzo, Alberto
core +1 more source