Results 31 to 40 of about 116,169 (348)

Structural Realism or Modal Empiricism?

open access: yesBritish Journal for the Philosophy of Science, 2019
Structural realism (SR) has been suggested as the best compromise in the debate on scientific realism. It proposes that we should be realist about the relational structure of the world, not its nature.
Quentin Ruyant
semanticscholar   +1 more source

Improving Likert scale big data analysis in psychometric health economics: reliability of the new compositional data approach

open access: yesBrain Informatics
Bipolar psychometric scales data are widely used in psychologic healthcare. Adequate psychological profiling benefits patients and saves time and costs. Grant funding depends on the quality of psychotherapeutic measures.
René Lehmann, Bodo Vogt
doaj   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

Empiricism, Stances, And The Problem Of Voluntarism [PDF]

open access: yes, 2011
Classical empiricism leads to notorious problems having to do with the (at least prima facie) lack of an acceptable empiricist justification of empiricism itself. Bas van Fraassen claims that his idea of the empirical stance can deal with such problems.
Baumann, Peter
core   +1 more source

Phenomenology, Empiricism, and Constructivism in Paolo Parrini's Positive Philosophy [PDF]

open access: yes, 2020
In this work, I discuss the role of Husserl’s phenomenology in Paolo Parrini’s positive philosophy. In the first section, I highlight the presence of both empiricist and constructivist elements in Parrini’s anti-foundationalist and anti-absolutist ...
Pace Giannotta, Andrea
core   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

Two Faces of Transcendental Empiricism: Gilles Deleuze and John McDowell

open access: yesRUDN Journal of Philosophy
The research presents a comparative analysis of John McDowell’s and Gilles Deleuze’s conceptions of transcendental empiricism. The very name of this conception bears in itself a kind of paradox, since Kant (the father of transcendental philosophy ...
Danila A. Volkov, Maksim D. Evstigneev
doaj   +1 more source

Au-delà de l’étiquette historiographique : l’empirisme singulier de J. N. Tetens

open access: yesAstérion, 2018
Beyond the usual conception of Johann Nikolaus Tetens as the “German Locke”, this paper wants to reassess the distinctive German context of the empiricist reference in the Essay on the Reform of the Speculative Philosophy (1775) and in the Philosophical ...
David Wittmann
doaj   +1 more source

Looking for Design in Materials Design

open access: yes, 2004
Despite great advances in computation, materials design is still science fiction. The construction of structure-property relations on the quantum scale will turn computational empiricism into true design.Comment: 3 pages, 1 ...
CS Smith   +5 more
core   +1 more source

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