Results 41 to 50 of about 28,200 (259)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Au-delà de l’étiquette historiographique : l’empirisme singulier de J. N. Tetens

open access: yesAstérion, 2018
Beyond the usual conception of Johann Nikolaus Tetens as the “German Locke”, this paper wants to reassess the distinctive German context of the empiricist reference in the Essay on the Reform of the Speculative Philosophy (1775) and in the Philosophical ...
David Wittmann
doaj   +1 more source

O projeto epistemológico empirista de Bas Van Fraassen: empirismo construtivo, epistemologia voluntarista, e empirismo estrutural [PDF]

open access: yes, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Filosofia e Ciências Humanas. Programa de Pós-Graduação em Filosofia, Florianópolis, 2013O presente trabalho versa sobre o projeto empirista de Bas van Fraassen, cuja obra é ...
Ferrador, Tiago Mathyas
core  

Tradisi Mamaq dalam Konteks Filsafat Pendidikan IPA Masa Depan

open access: yes, 2023
Tradisi mamaq oleh nenek moyang masyarakat suku Sasak merupakan suatu kegiatan mengunyah buah pinang,  kapur, daun  sirih, tembakau,  serta diakhiri dengan  nyusut.
Hardianti, Baiq Dina   +3 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Ceticismo de Hume através do Empirismo Transcendental de Deleuze: disjunção inclusiva e sujeito empírico

open access: yesDoisPontos, 2008
This article begins with an internal argument in the philosophy of Gilles Deleuze: every philosophy’s character might be evaluated by the immanence degree it accomplishes.
Hélio Rebello Cardoso Jr
doaj  

Ce qu’atteint l’expérience du vouloir : Hume, Locke, Malebranche

open access: yesAstérion, 2016
Starting from an excerpt of An Enquiry Concerning Human Understanding (section 7, part I), this article compares the conceptions that Hume, Locke and Malebranche uphold regarding the experience we have of the power of our will.
Sophie Bergont
doaj   +1 more source

Hermann Cohen and His Idea of the Logic of Pure Knowledge

open access: yesRUDN Journal of Philosophy, 2021
Hermann Cohen, as it is well known, criticised the Kantian notion of the thing-in-itself. And before him the Kantian thing-in-itself was criticised by Fichte and other German idealists.
Zinaida A. Sokuler
doaj   +1 more source

Analisis Faktor-Faktor Penyebab Rendahnya Minat Baca Siswa di Daerah Terpencil Terdepan dan Tertinggal

open access: yes, 2023
Aktivitas membaca adalah salah satu usaha untuk mendapatkan informasi atau sebuah pesan, atau menemukan pengetahuan baru yang tidak pernah dialami sebelumnya dan dapat dilakukan oleh semua orang di segala usia, seperti masyarakat umum, siswa dan anak pra
Amir, Amriani
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

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