Results 41 to 50 of about 118,227 (339)
Knowledge from Experience: The Rise of Empiricism [PDF]
Michael Stolberg
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Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Treating of bodies medical and political
Medicine was one of the chief empirical and philosophical sources for early modern political economy, helping to move analysis from moral to natural philosophy, and Mandeville was educated as a physician.
Harold J. Cook
doaj +1 more source
What’s wrong with the minimal conception of innateness in cognitive science? [PDF]
One of the classic debates in cognitive science is between nativism and empiricism about the development of psychological capacities. In principle, the debate is empirical. However, in practice nativist hypotheses have also been challenged for relying on
Ritchie, J. Brendan
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Phenomenology, Empiricism, and Constructivism in Paolo Parrini's Positive Philosophy [PDF]
In this work, I discuss the role of Husserl’s phenomenology in Paolo Parrini’s positive philosophy. In the first section, I highlight the presence of both empiricist and constructivist elements in Parrini’s anti-foundationalist and anti-absolutist ...
Pace Giannotta, Andrea
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Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
This article begins with an internal argument in the philosophy of Gilles Deleuze: every philosophy’s character might be evaluated by the immanence degree it accomplishes.
Hélio Rebello Cardoso Jr
doaj
The scientific method of Sir William Petty
An understanding of the precise nature of the scientific method of Sir William Petty has proved elusive to historians of economic thought, in no small part because of a lack of Petty's own characterization of his scientific approach.
James H. Ullmer
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Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
The Concept of Experience in Husserl's Phenomenology and James' Radical Empiricism [PDF]
In this paper, I develop a comparison between the philosophies of Husserl and James in relation to their concepts of experience. Whereas various authors have acknowledged the affinity between James’ early psychology and Husserl’s phenomenology, the late ...
Pace Giannotta, Andrea
core

