Results 51 to 60 of about 118,227 (339)

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

An Empirical Analysis of Perceptual Judgments

open access: yesThe Baltic International Yearbook of Cognition, Logic and Communication, 2014
This paper is a defense of Reformed Empiricism, especially against those critics who take Reformed Empiricism to be a viable account of empirical rationality only if it avails itself of certain rationalist assumptions that are inconsistent with ...
Nicholas Ray
doaj  

Does Neoclassical Econometrics Have a Scientific Foundation? A Critique Based on Hollis and Nell

open access: yesRevue Interventions Économiques, 2014
The 2008 global financial crisis has rekindled the debate over the scientific foundations of neo-Classical econometrics. Neo-Classical based econometrics interprets whatever it sees as individuals choosing with some degree of (perhaps bounded ...
Karim Errouaki
doaj   +1 more source

On the Possibility of Hallucinations [PDF]

open access: yes, 2020
Many take the possibility of hallucinations to imply that a relationalist account, according to which perceptual experiences are constituted by direct relations to ordinary mind-independent objects, is false.
Masrour, Farid
core  

Sustainable bioplastics manufacturing from renewable sources

open access: yesFEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto   +6 more
wiley   +1 more source

Time as an Empirical Concept in Special Relativity [PDF]

open access: yes, 2019
According to a widespread view, Einstein’s definition of time in his special relativity is founded on the positivist verification principle. The present paper challenges this received outlook.
Slavov, Matias Kimi
core  

Rationalism and Empiricism in Modern Medicine [PDF]

open access: yes, 2001
The roots of rationalism and empiricism in the Hippocratic tradition are explored. The triumph of the rationalists in the founding of modern medicine is emphasized. The development of clinical epidemiology and the evidence-based medicine over the last 30
Newton, Warren
core   +2 more sources

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Modal Empiricism and Two-Dimensional Semantics [PDF]

open access: yes, 2009
In the paper I argue that it follows from David Chalmers’ semantics and metaphysics concerning microphysical terms that microphysical identifications are strongly necessary.
Ambrus, Gergely
core  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

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