Results 111 to 120 of about 321,856 (312)

Disability and Occupation [PDF]

open access: yes, 2007
[Excerpt] It is well-documented that people with disabilities have a significantly lower rate of employment than people without disabilities (36% versus 74% according to the 2006 American Community Survey (ACS)).
Institute for Community Inclusion
core   +1 more source

Targeted H2S Delivery System Attenuates Blood‐Spinal Cord Barrier Disruption after Spinal Cord Injury by Reshaping the Ferritinophagy Pathway

open access: yesAdvanced Science, EarlyView.
The αvβ3‐mediated SPRC@MPDA‐RGD targets broken endothelial cells and controllably releases SPRC. CSE is then activated to produce endogenous H2S, which inhibits ferritinophagy. In brief, H2S inhibits autophagy by activating the PI3K/Akt/mTOR pathway, thereby suppressing the ferroptosis process mediated by NCOA4, and ultimately promoting the ...
Zhiheng Chen   +11 more
wiley   +1 more source

A survey of occupational therapists' involvement in facilitating self-employment for people with disabilities

open access: yesSouth African Journal of Occupational Therapy, 2018
  Background: In South Africa, occupational therapists are involved with the facilitation of people with disabilities ability to work, but the high unemployment rate in the country affects placement opportunities.
Luther Lebogang Monareng   +2 more
doaj   +1 more source

Assistive Technology at Work [PDF]

open access: yes, 2007
[Excerpt] Although an immediate transition into an institution of higher learning is ideal for some students who relied on assistive technology in high school, many make the decision to enter the workforce after graduation.
LD Online
core   +1 more source

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

open access: yesAdvanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak   +9 more
wiley   +1 more source

Employing those not expected to work: The stunning changes in the employment of single mothers and people with disabilities in the United States in the 1990s [PDF]

open access: yes, 2004
This report compares the dramatic changes in the level of government benefits provided to single mothers and people with disabilities, especially in the 1990s.
Burkhauser, Richard V.   +1 more
core   +1 more source

Estimates of prevalence, demographic characteristics and social factors among people with disabilities in the USA: a cross-survey comparison [PDF]

open access: yes, 2018
Objective: A national priority for disability research in the USA is the standardised identification of people with disabilities in surveillance efforts.
Houtenville, Andrew J., Lauer, Eric A.
core   +2 more sources

Cortical Somatostatin Neurons Regulate Seizure Susceptibility via MINAR1/Gαs–cAMP Signaling

open access: yesAdvanced Science, EarlyView.
Our study identifies MINAR1 as a novel regulator of cortical interneuron excitability and seizure susceptibility. MINAR1 is preferentially expressed in SST+ interneurons. Genetic ablation of MINAR1 leads to seizure hypersensitivity, reduced SST+ neuron excitability, and impaired Gαs–cAMP signaling, disrupting the E/I balance.
Wei‐Tang Liu   +20 more
wiley   +1 more source

Research Brief: Employer Practices and the Employment of People with Disabilities: Scoping the Literature [PDF]

open access: yes, 2014
Much of the literature about disability employment aimed at employers has consisted of checklists and recommendations of best practices that are loosely based on academic theories of diversity but lack research-based evidence of their efficacy.
Karpur, Arun, VanLooy, Sara
core   +1 more source

PVNCRF Neurons Regulate Migraine‐Like Allodynia by Activating CRFR2 on Spinal Trigeminal Caudalis Glutamatergic Neurons

open access: yesAdvanced Science, EarlyView.
Paraventricular CRF neurons in the hypothalamus project to glutamatergic neurons of the spinal trigeminal caudal nucleus, enhancing neuronal activation and CRFR2 signaling. This pathway increases CRF release and excitatory drive, promoting central sensitization and migraine‐related behaviors. Targeting the PVN–SP5C circuit provides a potential strategy
Jiang Bian   +13 more
wiley   +1 more source

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