Results 41 to 50 of about 3,456,694 (297)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Medical Specialization Exam in the Field of Child Health and Diseases Quota and Placement Trend Analysis (2013-2023)

Forbes Tıp Dergisi
Objective: This study aims to analyze the impact of changes in Medical Specialization Exam (TUS) quotas between 2013 and 2023 on occupancy rates across branches, focusing specifically on the specialization of pediatrics.
Mehmet KOCA
doaj   +1 more source

Current Experience of Graduates’ Career Planning and Its Use for Identifying Requirements and Setting Goals for Career Centers at Universities

Вестник Российского экономического университета имени Г. В. Плеханова, 2021
Every university graduate faces a problem of employment. A young specialist without work experience can hardly find a job by his/her specialization, which would allow them not only to use the acquired knowledge but also to get an adequate estimation of ...
A. M. Asaliev, E. S. Druzhinina
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Guaranteed Employment Plans

Law and Contemporary Problems, 1936
The mere mention of guaranteed employment is likely to excite widespread interest and support from those persons and groups who desire, through the enactment of state unemployment compensation laws, to prevent unemployment as well as to alleviate its effects.
openaire   +2 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Optimizing Data Interoperability: An Approach Towards Unified Employment Data in Indonesia [PDF]

SHS Web of Conferences
This research focuses on efforts to optimize data interoperability towards unified employment data in Indonesia, which consists of planning, manufacturing, integration, and marketing strategies using the Twitter social media account @kemnakerRI, which ...
Wahyuni Herpita, Mutiarin Dyah, Pribadi Ulung, Syakiran Akmal Ismail Nur, Priyo Purnomo Eko, Nurmandi Achmad, Kumorotomo Wahyudi, Ahdarrijal Yujitia   +7 more
doaj   +1 more source

Employment intention and career planning of male nursing students in different levels of colleges and universities: A qualitative study

Nursing Open, 2023
Aim To explore the employment intention and career planning of male nursing students at different levels of colleges and universities and provide references for formulating individualized training content.
Xiaoting Zeng, Fuxun Yang, Xinyi Xu, Tingting He, Shan Huang, Xiaoxiu Luo, Lihua Min   +6 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source