Results 51 to 60 of about 153,925 (307)
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Do family planning programmes help women's employment? The case of Indian mothers. IZA Discussion Paper No. 2762 [PDF]
, 2007 The paper deals with female employment in developing countries. We set out a model to test our argument that, at the first stage of development, demographic and health programs have proven to be more effective for women’s position in the society than ...
Francavilla, F., Giannelli, G.C.
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Planning for development: national physical development plan background paper: problems and deficiencies. National physical development plan background papers; no. N.P./BP2 [PDF]
, 2011 Examines the 'economic, social and physical conditions in light of the deficiencies' in various sectors across Trinidad and Tobago, including employment, income distribution, housing and so on, highlighting obstacles to ...
Government of the Republic of Trinidad and Tobago. Ministry of Finance (Planning and development).
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
The national physical development plan, Trinidad and Tobago. Volume II, Strategies and proposals [PDF]
, 2011 Presents alternative development strategies, spatial trends, planning proposals in the areas of land use, population and settlement, employment, agriculture, forestry, fishing, infrastructure, housing, tourism, environment and ...
Government of the Republic of Trinidad and Tobago. Ministry of Finance, Planning and Development.
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Synchronous online discussion: teaching English in higher education amidst the covid-19 pandemic
JEES (Journal of English Educators Society), 2020 During the outbreak of Covid-19 pandemic, many educational institutions have adapted various online teaching modes. However, studies exploring the employment of synchronous online discussion for teaching English in higher education context were still ...
Aji Budi Rinekso +1 more
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Urban regeneration, retail development and the role of information and communication technologies
Netcom, 2010 New urban planning concepts are progressive rather than radical perspectives from zoning to smart growth in the United States. In this respect, urban regeneration comes from adapting positive aspects from previous planning applications.
Eunseong Jeong +2 more
doaj +1 more source