Results 71 to 80 of about 153,925 (307)

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Avalon Peninsula study, Bay de Verde region [PDF]

open access: yes, 1971
Brigus Municipal Plan 1971Planning in Newfoundland -- Survey and analysis. Background. Location -- Physical setting -- History of development -- Population and employment. Population -- Employment -- Forecasts to 1981 -- Existing land use. General layout
Project Planning Associates
core  

Why Pakistan Must Break-into the Knowledge Economy

open access: yesLahore Journal of Economics
The author emphasizes in this paper that this was the moment in Pakistan’s economic trajectory for it to learn to leap frog technologically from a labor intensive economy, by passing the intermediate stages of resource based and scale based activities ...
Rashid Amjad
doaj  

Caregiving and Paid Employment in Suburbia: The Cases of Hamburg‐Oberbillwerder and Munich‐Freiham

open access: yesUrban Planning
Urban planning has long been criticised for privileging the spatial needs and demands of paid employment, thus discriminating against caregivers. This critique applied especially to monofunctional suburban districts that lacked childcare and employment ...
Henriette Bertram   +2 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Testing the ‘residential rootedness’ hypothesis of self-employment for Germany and the UK [PDF]

open access: yes, 2015
The work on this paper was funded by a Marie Curie grant from the European Commission within the 7th Framework Program (ID 252752).Based on the notion that entrepreneurship is a ‘local event’, the literature argues that entrepreneurs are ‘rooted’ in ...
Reuschke, Darja, Van Ham, Maarten
core   +1 more source

A portrait of accessibility change for four US metropolitan areas

open access: yesJournal of Transport and Land Use, 2016
Accessibility is a key objective of regional planning, one requiring the coordination of transportation and land use. Several metropolitan planning organizations in the United States and Europe have started to incorporate accessibility metrics into their
Louis A Merlin
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

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