Results 31 to 40 of about 374,243 (339)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

EMS Potentials in MENA region

Saudi Journal of Emergency Medicine, 2023
Background Emergency Medical Services (EMS) have been always considered as a vital service provided by of many Red Cross and Red Crescent (RCRC) national societies worldwide and in Middle East and North Africa (MENA) region in particular during emergency
Haytham Qosa, Mohamed Rashad Abdelaziz
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Comparing the Online Learning Capabilities of Gaussian ARTMAP and Fuzzy ARTMAP for Building Energy Management Systems [PDF]

, 2013
Recently, there has been a growing interest in the application of Fuzzy ARTMAP for use in building energy management systems or EMS. However, a number of papers have indicated that there are important weaknesses to the Fuzzy ARTMAP approach, such as ...
Howe, Joseph Mark, Mokhtar, Maizura
core   +1 more source

Switched Energy Management Strategy for Fuel Cell Hybrid Vehicle Based on Switch Network

Energies, 2020
Environmentally friendly and pollution-free fuel cell/lithium battery hybrid vehicles have received the attention of the community in recent years. It is imperative for fuel cell/lithium battery hybrid vehicles to use the energy management strategy (EMS)
Xu Chen, Guangdi Hu, Feng Guo, Mengqi Ye, Jingyuan Huang   +4 more
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Transduction of DNA information through water and electromagnetic waves

, 2014
The experimental conditions by which electromagnetic signals (EMS) of low frequency can be emitted by diluted aqueous solutions of some bacterial and viral DNAs are described.
Aïssa, Jamal, Capolupo, Antonio, Del Giudice, Emilio, Lavallee, Claude, Montagnier, Luc, Motschwiller, Steven, Polcari, Albino, Romano, Paola, Tedeschi, Alberto, Vitiello, Giuseppe   +9 more
core   +1 more source

The impact of using time critical intervention‐based dispatch thresholds on lowering lights and siren use to EMS 911 incidents

Journal of the American College of Emergency Physicians Open
Objectives Emergency Medical Services (EMS) has historically utilized lights and sirens (L&S) to respond to 911 incidents. L&S are used in 86% of scene responses nationally; however, time critical interventions (TCIs) occur in less than 7% of these ...
Jeffrey L. Jarvis, Danny Johns, Sydney E. Jarvis, Mike Knipstein, Taylor Ratcliff   +4 more
doaj   +1 more source

Community paramedicine program and outcomes of referred coronary artery bypass grafting patients

Rural and Remote Health
Introduction: Community paramedicine is a field in its infancy. The use of community paramedics has expanded in recent years as an alternative or adjunct to home health in the continued drive to decrease health disparities and complications. In current
Regan Washist, Casey Smith, Tyler Kientopf   +2 more
doaj   +1 more source

Novel clinical therapeutics targeting the epithelial to mesenchymal transition

Clinical and Translational Medicine, 2014
The epithelial to mesenchymal transition (EMT) is implicated in many processes, ranging from tissue and organogenesis to cancer and metastatic spread. Understanding the key regulatory mechanisms and mediators within this process offers the opportunity to
Anai N Kothari, Zhiyong Mi, Matthew Zapf, Paul C Kuo   +3 more
doaj   +1 more source