Results 31 to 40 of about 62,727 (249)

Gamma rays and EMS induced Flower Color Mutation in Grasspea (Lathyrus sativus Linn.)

open access: yesJournal of Agricultural Sciences, 2017
To induce flower color mutants in Grasspea (Lathyrus sativus Linn.) variety “Pusa-24“, the fresh seeds were exposed to 4 different doses of gamma radiation as physical mutagens (100, 200, 300 and 400 Gy) and treated with 4 different concentration of ...
Pegah Ramezani   +3 more
doaj   +1 more source

Induced chlorophyll mutations in Gloriosa superba

open access: yesElectronic Journal of Plant Breeding, 2021
The present experiment was carried out to study the spectrum of chlorophyll mutations, mutagenic effectiveness and efficiency in Gloriosa superba seeds using both chemical and physical mutagens.
S. Padmapriya* and K. Rajamani
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

The impact of using time critical intervention‐based dispatch thresholds on lowering lights and siren use to EMS 911 incidents

open access: yesJournal of the American College of Emergency Physicians Open
Objectives Emergency Medical Services (EMS) has historically utilized lights and sirens (L&S) to respond to 911 incidents. L&S are used in 86% of scene responses nationally; however, time critical interventions (TCIs) occur in less than 7% of these ...
Jeffrey L. Jarvis   +4 more
doaj   +1 more source

Community paramedicine program and outcomes of referred coronary artery bypass grafting patients

open access: yesRural and Remote Health
Introduction: Community paramedicine is a field in its infancy. The use of community paramedics has expanded in recent years as an alternative or adjunct to home health in the continued drive to decrease health disparities and complications. In current
Regan Washist   +2 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Novel clinical therapeutics targeting the epithelial to mesenchymal transition

open access: yesClinical and Translational Medicine, 2014
The epithelial to mesenchymal transition (EMT) is implicated in many processes, ranging from tissue and organogenesis to cancer and metastatic spread. Understanding the key regulatory mechanisms and mediators within this process offers the opportunity to
Anai N Kothari   +3 more
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Emergency Medical Services (EMS) Utilization in Zimbabwe: Retrospective Review of Harare Ambulance System Reports

open access: yesAnnals of Global Health, 2022
Background: Emergency medical services (EMS) are a critical but often overlooked component of essential public health care delivery in low- and middle-income countries (LMICs). Few countries in Africa have established EMS and there is scant literature to
Monalisa Muchatuta   +7 more
doaj   +1 more source

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