Results 41 to 50 of about 67,091 (268)

PSYNDEX Tests Review für ems - everyday memory survey - deutsche Fassung

open access: yes, 2023
This is a PSYNDEX Tests Review of ems - everyday memory survey - deutsche Fassung. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries.
Iwig, Clara
core   +1 more source

Decision to initiate transport to either Stroke Unit or local emergency department for patients with suspected stroke – a cohort study

open access: yesBMC Emergency Medicine
Background Timely access to specialized stroke treatment is critical for patient outcomes onset of stroke. In Region Zealand, Denmark, stroke care is centralized to a single Stroke Unit.
Morten Zacharias Plambech   +6 more
doaj   +1 more source

Efeitos biológicos da Pfaffia glomerata (Spreng.) Pedersen e da Pfaffia paniculata (Martius) Kuntze (Amaranthaceae)

open access: yesActa Scientiarum: Biological Sciences, 2008
A Pfaffia glomerata (Spreng.) Pedersen e da Pfaffia paniculata (Martius) Kuntze (Amaranthaceae) são plantas nativas da região alagada das ilhas de Porto Rico, Paraná, Brasil. São utilizadas na medicina popular como tônico, afrodisíaco e antidiabético.
Nádia Regina Alvim   +5 more
openaire   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Novel clinical therapeutics targeting the epithelial to mesenchymal transition

open access: yesClinical and Translational Medicine, 2014
The epithelial to mesenchymal transition (EMT) is implicated in many processes, ranging from tissue and organogenesis to cancer and metastatic spread. Understanding the key regulatory mechanisms and mediators within this process offers the opportunity to
Anai N Kothari   +3 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Amish Workarounds: Toward a Dynamic, Contextualized View of Technology Use

open access: yesThe Journal of Amish and Plain Anabaptist Studies, 2014
Interviews with northern Indiana Amish business owners reveal a tendency to create complex technological workarounds that allow them to abide by shared religious values while remaining competitive in the marketplace.
Lindsay Ems
doaj  

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

"The Collapse of the EMS: Symptomatic of a Doomed EMU?" [PDF]

open access: yes, 1995
In the soul searching following the tumult of the 1992 EMS crisis, observers and policy makers have been left wondering about its causes, and pondering the way forward to Economic and Monetary Union (EMU) in the context of the Maastricht Prescription. It
Velis, John O.
core  

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