Results 1 to 10 of about 338,860 (400)
Coupled Reversible and Irreversible Bistable Switches Underlying TGF-β-induced Epithelial to Mesenchymal Transition [PDF]
Epithelial to mesenchymal transition (EMT) plays important roles in embryonic development, tissue regeneration and cancer metastasis. While several feedback loops have been shown to regulate EMT, it remains elusive how they coordinately modulate EMT response to TGF-\beta treatment.
Tian, Xiao-Jun+2 more
arxiv +4 more sources
The significant parallels between cell plasticity during embryonic development and carcinoma progression have helped us understand the importance of the epithelial-mesenchymal transition (EMT) in human disease. Our expanding knowledge of EMT has led to a clarification of the EMT program as a set of multiple and dynamic transitional states between the ...
M. Angela Nieto+3 more
openaire +4 more sources
Quantifying cancer epithelial-mesenchymal plasticity and its association with stemness and immune response [PDF]
Cancer cells can acquire a spectrum of stable hybrid epithelial/mesenchymal (E/M) states during epithelial-mesenchymal transition (EMT). Cells in these hybrid E/M phenotypes often combine epithelial and mesenchymal features and tend to migrate collectively commonly as small clusters.
Bocci, Federico+7 more
arxiv +3 more sources
Enhanced Expression of Integrin αvβ3 Induced by TGF-β Is Required for the Enhancing Effect of Fibroblast Growth Factor 1 (FGF1) in TGF-β-Induced Epithelial-Mesenchymal Transition (EMT) in Mammary Epithelial Cells. [PDF]
Epithelial-to-mesenchymal transition (EMT) plays a critical role in cancer metastasis, and is regulated by growth factors such as transforming growth factor β (TGF-β) and fibroblast growth factors (FGF) secreted from the stromal and tumor cells. However,
Hamada, Yoshinosuke+7 more
core +14 more sources
Particle and radiation sources are widely employed in manifold applications. In the last decades, the upcoming of versatile, energetic, high-brilliance laser-based sources, as produced by intense laser–matter interactions, has introduced utilization of ...
Pilar Puyuelo-Valdes+7 more
doaj +1 more source
Linearizing Nonlinear Optics [PDF]
Fourier nonlinear optics merges the simplicity of linear optics with the power of nonlinear optics to achieve a decoupling of frequencies, amplitudes and phases in nonlinear processes - enabling first deep UV shaping at 207nm.
Bruno E. Schmidt+6 more
doaj +1 more source
Epithelial-Mesenchymal-Plasticity (EMP) is an intrinsic, dynamic and reversible phenotypic modulation exhibited by early embryonic cells. Several key cellular movements that determine the fate of an embryo or dictate development of an organ or healing of a wound are dependent on EMP.
Lalita A. Shevde, Rajeev S. Samant
openaire +3 more sources
Tutorial: Circuit-based Electromagnetic Transient Simulation [PDF]
The growing penetration of inverter-based resources and associated controls necessitates system-wide electromagnetic transient (EMT) analyses. EMT tools and methods today were not designed for the scale of these analyses. In light of the emerging need, there is a great deal of interest in developing new techniques for fast and accurate EMT simulations ...
arxiv +1 more source
Peak power & average power scaling via fourier domain OPA (FOPA) [PDF]
FoTaking advantage of pulse shortening upon amplification, we demonstrate 2.5TW pulses (30mJ, 2 cycle, 1.8 μm) based on TiSa pumping, while for boosting average power we utilize a 500W Yb platform for pump and seed pulses.
Bruno E. Schmidt+11 more
doaj +1 more source