Results 31 to 40 of about 202,867 (295)

EMT and tumor metastasis [PDF]

open access: yesClinical and Translational Medicine, 2015
AbstractEMT and MET comprise the processes by which cells transit between epithelial and mesenchymal states, and they play integral roles in both normal development and cancer metastasis. This article reviews these processes and the molecular pathways that contribute to them. First, we compare embryogenesis and development with cancer metastasis.
Heerboth, Sarah   +7 more
openaire   +5 more sources

Transcriptional control of epithelial to mesenchymal transition by regulatory factors and epigenetic mechanisms [PDF]

open access: yes, 2011
The World Health Organization (WHO) states cancer to be a leading cause of death worldwide accounting for 7.6 million deaths (around 13% of all deaths) and is projected rising to over 11 million in 2030.
Tiwari, Neha
core   +1 more source

EMT and Anti-EMT Strategies in Cancer

open access: yesJournal of Cancer Therapy, 2015
This article discusses the role of epithelial mesenchymal transition (EMT) and addresses the scientific merits on epigenetic regulation of EMT. The importance of EMT as a prognostic biomarker is explored and the rationale on application of multitargeted epigenetic therapy is discussed. We describe a literature review of the epigenetic influence of such
M. A. Nezami   +2 more
openaire   +2 more sources

EMT or EMT-Promoting Transcription Factors, Where to Focus the Light? [PDF]

open access: yesFrontiers in Oncology, 2014
The epithelial-to-mesenchymal transition (EMT) is commonly considered as a main driving force of the metastatic cascade. An impressive series of experiments and observations worldwide supports its pivotal role in promoting cancer cell dissemination at the invasive fronts of tumors, intravasation, cell survival in fluids, and extravasation, with ...
Stéphane eAnsieau   +14 more
openaire   +3 more sources

Angular Parameters Estimation of Multiple Incoherently Distributed Sources Generating Noncircular Signals

open access: yesIEEE Access, 2019
In this paper, we introduce for the first time a new method for the estimation of the angular parameters [i.e., central directions of arrival (DOAs) and angular spreads] of multiple non-circular and incoherently-distributed (ID) sources.
Sonia Ben Hassen   +3 more
doaj   +1 more source

Review of methods for coding of speech signals

open access: yesEURASIP Journal on Audio, Speech, and Music Processing, 2023
Speech is the most common form of human communication, and many conversations use digital communication links. For efficient transmission, acoustic speech waveforms are usually converted to digital form, with reduced bit rates, while maintaining decoded ...
Douglas O’Shaughnessy
doaj   +1 more source

Spectro-Temporal Electrocardiogram Analysis for Noise-Robust Heart Rate and Heart Rate Variability Measurement

open access: yesIEEE Journal of Translational Engineering in Health and Medicine, 2017
The last few years has seen a proliferation of wearable electrocardiogram (ECG) devices in the market with applications in fitness tracking, patient monitoring, athletic performance assessment, stress and fatigue detection, and biometrics, to name a few.
Diana P. Tobon   +2 more
doaj   +1 more source

EMT-cortex attachment in WT and clasp-1.

open access: yes, 2018
EMT-cortex attachment in WT and clasp-1.
Chris Ambrose (197508)   +1 more
core   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

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