Results 51 to 60 of about 303,325 (299)
Capsaicin triggers autophagic cell survival which drives epithelial mesenchymal transition and chemoresistance in bladder cancer cells in an Hedgehog-dependent manner [PDF]
, 2016 Bladder cancer (BC) is a common urologic tumor characterized by high risk of recurrence and mortality. Capsaicin (CPS), used as an intravesical drug for overactive bladder, was demonstrated to induce cell death in different cancer cells including BC ...
Amantini, C +6 more
core +1 more source
The 'alternative' EMT switch [PDF]
Breast Cancer Research, 2011 Epithelial to mesenchymal transition (EMT) is an essential process in embryonic development and is aberrantly induced in many disease settings. Work carried out by Chonghui Cheng's laboratory addressed the involvement of alternative RNA splicing in EMT and its link to tumour progression. They describe a switch in CD44 expression from variant isoform(s)
Klingbeil, Pamela, Isacke, Clare M
openaire +2 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
IEEE AccessDeep neural network (DNN) classifiers are potent instruments that can be used in various security-sensitive applications. Nonetheless, they are vulnerable to certain attacks that impede or distort their learning process.
Orson Mengara +2 more
doaj +1 more source
Tumor Budding: The Name is EMT. Partial EMT. [PDF]
Journal of Clinical Medicine, 2016 Tumor budding is a histological phenomenon encountered in various cancers, whereby individual malignant cells and/or small clusters of malignant cells are seen in the tumor stroma. Postulated to be mirror epithelial-mesenchymal transition, tumor budding has been associated with poor cancer outcomes.
Alexandru Grigore +4 more
openaire +3 more sources
Epithelial–Mesenchymal Transition (EMT)
International Journal of Molecular Sciences, 2023 Epithelial–mesenchymal transition (EMT) is a cellular process involved in many physiological and pathological conditions [...]
Guidalberto Manfioletti, Monica Fedele
openaire +4 more sources
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Sensors, 2019 We propose a new collaborative beamforming (CB) solution robust (i.e., RCB) against major channel estimation impairments over dual-hop transmissions through a wireless sensor network (WSN) of K nodes. The source first sends its signal to the WSN.
Oussama Ben Smida +3 more
doaj +1 more source
The Energy-Momentum Tensor for Cosmological Perturbations [PDF]
, 1997 We study the effective energy-momentum tensor (EMT) for cosmological perturbations and formulate the gravitational back-reaction problem in a gauge invariant manner.
A. A. Starobinsky +31 more
core +2 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source