Results 61 to 70 of about 202,867 (295)

MSPB: a longitudinal multi-sensor dataset with phenotypic trait measurements from honey bees

open access: yesScientific Data
We present a one-year-long multi-sensor dataset collected from honey bee colonies (Apis mellifera) with rich phenotypic measurements. Data were collected non-stop from April 2020 to April 2021 from 53 hives located at two apiaries in Québec, Canada.
Yi Zhu   +6 more
doaj   +1 more source

Coupling-Strength-Independent Long-Period Grating Designs for THz-Bandwidth Optical Differentiators

open access: yesIEEE Photonics Journal, 2013
A novel design of THz-bandwidth all-optical arbitrary-order temporal differentiators using long period fiber/waveguide gratings (LPGs) is proposed and numerically demonstrated.
Reza Ashrafi, Ming Li, Jose Azana
doaj   +1 more source

TableE13-Pseudo-bulk-of-scRNA-seq-EMT-differential-lncRNA-expression-list.xlsx

open access: yes, 2022
TableE13-Pseudo-bulk-of-scRNA-seq-EMT-differential-lncRNA-expression-list ...
Adam Williams (12021065)   +1 more
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Reconfigurable photonic generation of broadband chirped waveforms using a single CW laser and low-frequency electronics

open access: yesNature Communications, 2018
Producing versatile radio-frequency chirped waveforms often requires complicated techniques. The authors use a fiber-optic frequency-shifting loop to create a low-complexity photonic chirp generator with high bandwidth and fully flexible properties for ...
Hugues Guillet de Chatellus   +4 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Plant/Bacterial Virus-Based Drug Discovery, Drug Delivery, and Therapeutics

open access: yesPharmaceutics, 2019
Viruses have recently emerged as promising nanomaterials for biotechnological applications. One of the most important applications of viruses is phage display, which has already been employed to identify a broad range of potential therapeutic peptides ...
Esen Sokullu   +2 more
doaj   +1 more source

Meta-Analysis of EMT Datasets Reveals Different Types of EMT

open access: yesPLOS ONE, 2016
As a critical process during embryonic development, cancer progression and cell fate conversions, epithelial-mesenchymal transition (EMT) has been extensively studied over the last several decades. To further understand the nature of EMT, we performed meta-analysis of multiple microarray datasets to identify the related generic signature. In this study,
Lining Liang   +6 more
openaire   +4 more sources

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

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