Results 101 to 110 of about 187,158 (266)

Meta-Analysis of EMT Datasets Reveals Different Types of EMT.

, 2016
As a critical process during embryonic development, cancer progression and cell fate conversions, epithelial-mesenchymal transition (EMT) has been extensively studied over the last several decades.
Wei Zhang, Rui Kuang, Lining Liang, Wei Zhang (405), Xiao Yang (19898), Mengdan Zhang, Lining Liang (2817292), Hao Sun, Rui Kuang (74290), Xiao Yang, Hui Zheng (58412), Mengdan Zhang (2817295), Hui Zheng, Hao Sun (14095)   +13 more
core   +1 more source

Millimeter-Wave Joint Sensing and Communication System Design for Connected Automated Vehicles

IEEE Access
This paper introduces a novel mmWave joint radar and communication (JRC) system operating in the 24 GHz ISM band, specifically designed for automated connected vehicles. The system utilizes a single transceiver platform featuring a frequency-shift keying
Nima Souzandeh, Mehrdad Harifi-Mood, Sonia Aissa, Serioja Ovidiu Tatu   +3 more
doaj   +1 more source

Androgen Receptor‐Induced Lactoferrin Accelerates Prostate Tumorigenesis Through Modulating Ferroptosis

Advanced Science, EarlyView.
This study demonstrates that transcription factor androgen receptor (AR) directly binds the LF promoter, driving lactoferrin overexpression to promote ferritin (FTH1/FTL) upregulation and inhibit p53‐ALOX12‐mediated ferroptosis in prostate cancer. Lactoferrin could be a new potential therapeutic target in prostate cancer.
Can Liu, Qiu Peng, Xiaoyue Zhang, Zhengshuo Li, Yangge Wu, Yuqing Wen, Run Zheng, Shuanglong Wu, Chenfei Zhou, Zhengyu Hu, Lanjun Shu, Xinyi Ma, Qiuyang Li, Ya Ma, Chunlin Ou, Ming Zhao, Songqing Fan, Lingyu Wei, Jian Ma   +18 more
wiley   +1 more source

The application of respiratory muscle training to competitive rowing

, 2010
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Respiratory muscle training (RMT) has been shown to improve exercise tolerance during a wide range of exercise modalities and durations of activity ...
Griffiths, Lisa Ann
core  

Clustering EMT-induction samples.

, 2016
(A-B) 74 human and 31 mouse EMT-induction samples were grouped into clusters by the expression profiles. The correlations among pairs of samples were shown in (A) for human and (B) for mouse.
Rui Kuang (74290), Wei Zhang (405), Xiao Yang (19898), Hui Zheng (58412), Mengdan Zhang (2817295), Hao Sun (14095), Lining Liang (2817292)   +6 more
core   +1 more source

TSPYL5 Promotes Triple‐Negative Breast Cancer Metastasis by Antagonizing USP10‐Mediated PTEN Stabilization to Unleash a ZEB1‐Dependent EMT Program

Advanced Science, EarlyView.
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi, Ming Yi, Shengyu Xie, Zhaokun Wang, Xinyue Zhang, Yangwei Zhang, Rui Tang, Yuan Yang, Yunqiang Liu   +8 more
wiley   +1 more source

Numerical Modeling of a Low-Cobalt All-Solid-State Cell with Ceramic Electrolyte Using a Deformable Geometry

Batteries
All-solid-state batteries with a lithium negative electrode and a ceramic electrolyte are key toward high energy density. To ensure a safe, fast, accurate, and cost-effective development of this technology, the experimental methodology must be supported ...
David Nadeau, Lionel Roué, François Allard   +2 more
doaj   +1 more source

Full‐Body AI Agent: A Perspective on Multi‐Scale Collaborative AI for Systemic Biology and Precision Medicine

Advanced Science, EarlyView.
We propose the Full‐Body AI Agent, a multi‐scale collaborative framework with 7 biological‐layer agents. It unifies multi‐omics/clinical data via standardized protocols, enabling phenotype‐guided closed‐loop reasoning, quantitative evaluation, and LLM safeguards, with promising applications in tumor metastasis modeling and precision drug development ...
Aoqi Wang, Jiajia Liu, Jianguo Wen, Yangyang Luo, Zhiwei Fan, Liren Yang, Xi Hu, Ruihan Luo, Yankai Yu, Sophia Li, Weiling Zhao, Xiaobo Zhou   +11 more
wiley   +1 more source

Bioprinted Tumor Microenvironment Models Reveal Immune Evasion and Guide CAR‐NK Therapeutic Strategies

Advanced Science, EarlyView.
This study presents a 3D embedded bioprinting platform that recapitulates key stromal features of the tumor microenvironment using fibroblasts and lung‐derived ECM. The model enables functional assessment of CAR‐NK cells and provides a versatile tool to support the development of next‐generation immunotherapeutic strategies against solid tumors ...
Dahong Kim, Seona Jo, In‐Hwan Jang, Yu‐Jin Kim, Youngmee Jung, Junhyoung Ahn, Hyungjun Lim, Jae Jong Lee, Kangwon Lee, Tae‐Don Kim, Su A Park   +10 more
wiley   +1 more source

Epithelial-to-Mesenchymal Transition (EMT) in experimental intestinal fibrosis

, 2015
Inflammatory Bowel Diseases (IBD) are chronic and progressive inflammatory disorders that may result in intestinal fibrosis, characterized by excessive and uncontrolled deposition of extracellular matrix components (ECM).
LATELLA, GIOVANNI, De Berardinis, Luca, VETUSCHI, ANTONELLA, FLATI, VINCENZO, SFERRA, ROBERTA, DI GREGORIO, JACOPO, POMPILI, SIMONA   +6 more
core   +1 more source