Results 91 to 100 of about 303,325 (299)

Effective energy-momentum tensor of strong-field QED with unstable vacuum

open access: yes, 2007
We study the influence of a vacuum instability on the effective energy-momentum tensor (EMT) of QED, in the presence of a quasiconstant external electric field, by means of the relevant Green functions.
Fradkin E S   +6 more
core   +6 more sources

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Reversing EMT

open access: yesKidney International, 2005
Epithelial-mesenchymal transition (EMT) is a process whereby epithelial cell layers lose polarity and cell-cell contacts and undergo a massive cytoskeleton reorganization involving the rho family and the remodeling of the actin microfilament mesh (Thiery, 2002).
openaire   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Laser-driven proton sources for efficient radiation testing

open access: yesScientific Reports
Several fields such as particle physics, space exploration, and high-energy physics, use Commercial Off-The-Shelf (COTS) electronic components in a high-radiation operative environment.
Beatrice D’Orsi   +20 more
doaj   +1 more source

Real-time gap-free dynamic waveform spectral analysis with nanosecond resolutions through analog signal processing

open access: yesNature Communications, 2020
Real-time dynamic Fourier analysis of high-speed signals is difficult using either digital or analog schemes. Here, the authors present a universal analog approach that can track the changing frequency spectrum of waveforms in a real-time fashion at the ...
Saikrishna Reddy Konatham   +7 more
doaj   +1 more source

On the hadron mass decomposition

open access: yes, 2017
We argue that the standard decompositions of the hadron mass overlook pressure effects, and hence should be interpreted with great care. Based on the semiclassical picture, we propose a new decomposition that properly accounts for these pressure effects.
Lorcé, Cédric
core   +3 more sources

Mechanoregulatory Effects of Cell‐Scale Microwells on Epithelial Cell Phenotype

open access: yesAdvanced Functional Materials, EarlyView.
In small polycaprolactone microwells, A549 epithelial cells span well edges, in contrast to cells growing on flat substrates. Focal adhesion sites (yellow) concentrate at topographic boundaries, while cytoskeletal tension (magenta stress fibers) is transmitted to the nucleus (blue), reducing nuclear sphericity.
Ruiwen He   +10 more
wiley   +1 more source

Electrification of Madrid Fleet Public Transport Company (EMT-Madrid): Strategic Analysis and Implementation

open access: yesInternational Journal of Production Management and Engineering, 2019
Madrid Public Transport Company (EMT-Madrid) is a property of the Madrid City Council, and it provides the public buses service in the whole city.
J. García Hernanz   +4 more
doaj   +1 more source

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