Results 151 to 160 of about 202,867 (295)

SZÁMOKT 2004 : XIV. Számítástechnika az Oktatásban Nemzetközi Konferencia

, 2004
Kolozsváron 2004. március 25-28. között az Erdélyi Magyar Műszaki Tudományos Társaság (EMT) Számítástechnikai Szakosztálya által megrendezésre került Számítástechnika és Oktatás Konferencia (SZÁMOKT) programja és előadásainak írásos ...

core  

GSTM4 Suppresses Prostate Cancer Progression by Targeting TRIM27‐mediated ACLY Ubiquitination and Lipid Metabolism

Advanced Science, EarlyView.
GSTM4 enhances the interaction between ACLY and the E3 ubiquitin ligase TRIM27, thereby increasing K48‐linked ubiquitination at the K554 site of ACLY and promoting its degradation. Consequently, GSTM4 regulates lipid synthesis, as well as the proliferation and metastasis of PCa cells, by modulating ACLY stability.
Kang‐Ping Xiong, Fei Liu, Wang Wang, Gang Wang, Kai‐Yu Qian, Sheng Tu, Si‐Ming Chen, Hui‐Min Xu, Shan‐Shan Zhang, Yong Li, Xing‐Huan Wang, Hong Weng   +11 more
wiley   +1 more source

Epithelial-mesenchymal transition in carcinoma: navigating phenotypic states to target resistance and metastasis. [PDF]

Cancer Metastasis Rev
Wang X, Zhang CX, Zhao Y, He J, Thiery JP.   +4 more
europepmc   +1 more source

The Cancer Cell Metabolic Reprogramming Remodels the Tumor Microenvironment: Molecular Mechanisms and Therapeutic Strategies

Advanced Science, EarlyView.
This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang, Zhicheng Zhou, Xue Jiang, Zhenguang Du, Yangyang Zhan, Xinli Liu   +5 more
wiley   +1 more source

Role of epithelial-mesenchymal transition (EMT) in malignancies: current status and future prospects. [PDF]

Signal Transduct Target Ther
Meftahpour V, Dakal TC, Maciaczyk J, Sharma A, Schmidt-Wolf IGH.   +4 more
europepmc   +1 more source

Space Jam‐Ming: Generating Interstitial Space Using Fragmented Granular GelMA to Investigate Novel Paradigms of Cancer Metastasis

Advanced Science, EarlyView.
Microgels enable independent control of stiffness and interstitial space, overcoming limitations of conventional 3D hydrogels. Using fragmented gelatin methacryloyl microgels, we show that stiffness does not restrict non‐metastatic breast cancer growth, contrary to bulk hydrogels, and reveal the role of adherent‐to‐suspension transition in cancer ...
Danielle Vahala, Zhuang Min Lee, Sebastian E. Amos, Dong Woo Son, Jong Hwa Byun, Farzan Navaeipour, Jiayue Li, Kai L. Metzner, Ji Hoon Jeong, Juyeon Kim, Yongsung Hwang, Brendan F. Kennedy, Khoon S. Lim, Hee Seung Lee, Hyun Woo Park, Yu Suk Choi   +15 more
wiley   +1 more source

A Systems View of Posterior Capsule Opacification: TGF-β/ROS Signaling, Mitochondrial Homeostasis, and Injury/Aging Cues-Therapeutic Opportunities. [PDF]

Invest Ophthalmol Vis Sci
Xu K, Huang R, Xie H, Du L, Liu M, Wang J, Chen C.   +6 more
europepmc   +1 more source

AARS1‐Mediated H3K27 Lactylation Rewires Glycolysis to Sustain Aggressive and Recurrent Bladder Cancer

Advanced Science, EarlyView.
AARS1 drives PI3K–AKT–mTOR‐dependent glycolysis in bladder cancer, promoting lactate accumulation, increased lactylation, H3K27la enrichment at the HK2 promoter, and HK2 transcription. HK2 reinforces glycolysis, sustaining a metabolic–epigenetic program associated with tumor progression, recurrence, and metastasis.
Qin Yuan, Tianbao Song, Yipeng He, Sihan Xia, Yaoqiu Huang, Wenlin He, Qin Yi, Zefeng Wang, Peihan Wang, Chenbo Huang, Linzhi Li, Zhen Yin, Fan Cheng, Weimin Yu   +13 more
wiley   +1 more source

Efficacy of endometrial microbiota testing-guided personalized therapy in infertile women stratified by CD138 status: a retrospective cohort study. [PDF]

Front Endocrinol (Lausanne)
He F, Peng E, Lin J, Mao Z, Lu X, Xu H, Guo L, Zou Y, Wang J, Lu S, Huang X.   +10 more
europepmc   +1 more source

SZÁMOKT 2006 : Számítástechnika az Oktatásban XVI. Nemzetközi Konferencia

, 2006
Szovátán 2006. május 25-28. között az Erdélyi Magyar Műszaki Tudományos Társaság (EMT) Számítástechnikai Szakosztálya által megrendezésre került Számítástechnika és Oktatás Konferencia (SZÁMOKT) programfüzete és előadásainak írásos ...

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