Results 11 to 20 of about 366,025 (373)
Epithelial–Mesenchymal Transition (EMT) 2021
International Journal of Molecular Sciences, 2022 Epithelial–mesenchymal transition (EMT) is a transdifferentiation process wherein epithelial cells acquire characteristics typical of mesenchymal cells [...]
Guidalberto Manfioletti, Monica Fedele
openaire +4 more sources
Renal protective effects of empagliflozin via inhibition of EMT and aberrant glycolysis in proximal tubules [PDF]
JCI Insight, 2020 SGLT2 inhibitors are beneficial in halting diabetic kidney disease; complete mechanisms is unknown. The epithelial to mesenchymal transition (EMT) is associated with Sirt3 suppression and aberrant glycolysis.
Jinpeng Li +8 more
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The molecular mechanisms and therapeutic strategies of EMT in tumor progression and metastasis
Journal of Hematology & Oncology, 2022 Epithelial–mesenchymal transition (EMT) is an essential process in normal embryonic development and tissue regeneration. However, aberrant reactivation of EMT is associated with malignant properties of tumor cells during cancer progression and metastasis,
Yuhe Huang, Weiqi Hong, Xiawei Wei
semanticscholar +1 more source
Dynamic EMT: a multi‐tool for tumor progression
EMBO Journal, 2021 The process of epithelial–mesenchymal transition (EMT) is fundamental for embryonic morphogenesis. Cells undergoing it lose epithelial characteristics and integrity, acquire mesenchymal features, and become motile.
S. Brabletz +3 more
semanticscholar +1 more source
RHOJ controls EMT-associated resistance to chemotherapy
Nature, 2023 RHOJ regulates epithelial-to-mesenchymal-transition-associated resistance to chemotherapy by enhancing the response to replicative stress and activating the DNA damage response, enabling tumour cells to rapidly repair DNA lesions induced by chemotherapy.
Maud Debaugnies +17 more
semanticscholar +1 more source
Vimentin Is at the Heart of Epithelial Mesenchymal Transition (EMT) Mediated Metastasis
Cancers, 2021 Simple Summary Vimentin is an important filamentous protein providing structural and functional support to the cell. During initial stages of cancer development, vimentin concentration is very low, however, it increases when cancer starts to invade the ...
Saima Usman +6 more
semanticscholar +1 more source
Cells, 2021 The epithelial–mesenchymal transition (EMT) is an essential event during cell development, in which epithelial cells acquire mesenchymal fibroblast-like features including reduced intercellular adhesion and increased motility.
G. Marconi +6 more
semanticscholar +1 more source
EMT/MET plasticity in cancer and Go-or-Grow decisions in quiescence: the two sides of the same coin?
Molecular Cancer, 2023 Epithelial mesenchymal transition (EMT) and mesenchymal epithelial transition (MET) are genetic determinants of cellular plasticity. These programs operate in physiological (embryonic development, wound healing) and pathological (organ fibrosis, cancer ...
Azamat Akhmetkaliyev +3 more
semanticscholar +1 more source
Cell Proliferation, 2023 Epithelial–mesenchymal transition (EMT) or mesenchymal–epithelial transition (MET) plays critical roles in cancer metastasis. Recent studies, especially those based on single‐cell sequencing, have revealed that EMT is not a binary process, but a ...
Dandan Li +7 more
semanticscholar +1 more source
Inducers of epithelial mesenchymal transition and cancer stem cells in malignant pleural effusions [PDF]
, 2016 The Epithelial to Mesenchymal Transition (EMT) plays a role not only in tumor metastasis but also in tumor recurrence. This process is believed to be tightly linked to the presence of Cancer Stem Cells (CSCs) however, it is still not clear which ...
Cherubini, Emanuela +5 more
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