Results 21 to 30 of about 213,806 (248)

EMT, MET, Plasticity, and Tumor Metastasis.

open access: yesTrends in Cell Biology, 2020
Cancer cell identity and plasticity are required in transition states, such as epithelial-mesenchymal transition (EMT) and mesenchymal-epithelial transition (MET), in primary tumor initiation, progression, and metastasis. The functional roles of EMT, MET,
Basil Bakir   +3 more
semanticscholar   +1 more source

Single-cell lineage tracing of metastatic cancer reveals selection of hybrid EMT states.

open access: yesCancer Cell, 2021
The underpinnings of cancer metastasis remain poorly understood, in part due to a lack of tools for probing their emergence at high resolution. Here we present macsGESTALT, an inducible CRISPR-Cas9-based lineage recorder with highly efficient single-cell
K. Simeonov   +8 more
semanticscholar   +1 more source

Identification of EMT signaling cross-talk and gene regulatory networks by single-cell RNA sequencing

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2021
Significance The epithelial-to-mesenchymal transition (EMT) is a critical cell biological process that occurs during normal embryonic development and cancer progression.
Abhijeet P. Deshmukh   +11 more
semanticscholar   +1 more source

Decoupling Frequencies, Amplitudes and Phases in Nonlinear Optics

open access: yesScientific Reports, 2017
In linear optics, light fields do not mutually interact in a medium. However, they do mix when their field strength becomes comparable to electron binding energies in the so-called nonlinear optical regime.
Bruno E. Schmidt   +6 more
doaj   +1 more source

EMT, cancer stem cells and autophagy; The three main axes of metastasis.

open access: yesBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020
Epithelial-mesenchymal transition (EMT) and Cancer stem-like cells (CSCs) are major factors contributing to the metastasis of cancer cells. Consequently, the signaling pathways involved in both processes are appropriate therapeutic targets in the ...
G. Babaei   +2 more
semanticscholar   +1 more source

EMT mechanism in breast cancer metastasis and drug resistance: Revisiting molecular interactions and biological functions.

open access: yesBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022
One of the malignant tumors in women that has involved both developed and developing countries is breast cancer. Similar to other types of tumors, breast cancer cells demonstrate high metastatic nature.
M. Hashemi   +13 more
semanticscholar   +1 more source

Laser-accelerated particle beams for stress testing of materials

open access: yesNature Communications, 2018
Recently, there has been significant progress on the application of laser-generated proton beams in material science. Here the authors demonstrate the benefit of employing such beams in stress testing different materials by examining their mechanical ...
M. Barberio   +10 more
doaj   +1 more source

Quantitative laser-based x-ray fluorescence and particle-induced x-ray emission

open access: yesNew Journal of Physics, 2022
In this work, we demonstrate the feasibility of quantitative laser-based x-ray fluorescence (XRF) combined with particle-induced x-ray emission (PIXE) (called XPIF for x-ray and particle-induced fluorescence) spectroscopy analysis for elemental ...
Frédéric Boivin   +4 more
doaj   +1 more source

Audio-Visual Multimedia Quality Assessment: A Comprehensive Survey

open access: yesIEEE Access, 2017
Measuring perceived quality of audio-visual signals at the end-user has become an important parameter in many multimedia networks and applications. It plays a crucial role in shaping audio-visual processing, compression, transmission and systems, along ...
Zahid Akhtar, Tiago H. Falk
doaj   +1 more source

Autophagy and EMT in cancer and metastasis: Who controls whom?

open access: yesBiochimica et Biophysica Acta - Molecular Basis of Disease, 2022
Metastasis consists of hallmark events, including Epithelial-Mesenchymal Transition (EMT), angiogenesis, initiation of inflammatory tumor microenvironment, and malfunctions in apoptosis. Autophagy is known to play a pivotal role in the metastatic process.
R. Gundamaraju   +8 more
semanticscholar   +1 more source

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