Results 31 to 40 of about 366,025 (373)

LARP7 suppresses P-TEFb activity to inhibit breast cancer progression and metastasis. [PDF]

open access: yes, 2014
Transcriptional elongation by RNA polymerase (Pol) II is essential for gene expression during cell growth and differentiation. The positive transcription elongation factor b (P-TEFb) stimulates transcriptional elongation by phosphorylating Pol II and ...
Ji, Xiaodan   +3 more
core   +3 more sources

Decoupling Frequencies, Amplitudes and Phases in Nonlinear Optics

open access: yesScientific Reports, 2017
In linear optics, light fields do not mutually interact in a medium. However, they do mix when their field strength becomes comparable to electron binding energies in the so-called nonlinear optical regime.
Bruno E. Schmidt   +6 more
doaj   +1 more source

Phenotypic heterogeneity driven by plasticity of the intermediate EMT state governs disease progression and metastasis in breast cancer

open access: yesbioRxiv, 2022
The Epithelial-to-Mesenchymal Transition (EMT) is a dynamic cellular program that is co-opted by cancer cells to enhance, among others, migratory and invasive cell traits. It is a key contributor to heterogeneity, chemo-resistance, and metastasis in many
Meredith S. Brown   +10 more
semanticscholar   +1 more source

Laser-accelerated particle beams for stress testing of materials

open access: yesNature Communications, 2018
Recently, there has been significant progress on the application of laser-generated proton beams in material science. Here the authors demonstrate the benefit of employing such beams in stress testing different materials by examining their mechanical ...
M. Barberio   +10 more
doaj   +1 more source

Quantitative laser-based x-ray fluorescence and particle-induced x-ray emission

open access: yesNew Journal of Physics, 2022
In this work, we demonstrate the feasibility of quantitative laser-based x-ray fluorescence (XRF) combined with particle-induced x-ray emission (PIXE) (called XPIF for x-ray and particle-induced fluorescence) spectroscopy analysis for elemental ...
Frédéric Boivin   +4 more
doaj   +1 more source

TGFβ impairs HNF1α functional activity in Epithelial-to-Mesenchymal Transition interfering with the recruitment of CBP/p300 acetyltransferases [PDF]

open access: yes, 2019
The cytokine transforming growth factor β (TGFβ) plays a crucial role in the induction of both epithelial-to-mesenchymal transition (EMT) program and fibro-cirrhotic process in the liver, where it contributes also to organ inflammation following several ...
Amicone, Laura   +8 more
core   +1 more source

MicroRNAs and epithelial-mesenchymal transition in prostate cancer. [PDF]

open access: yes, 2016
Prostate cancer (PCa) is a leading cause of male cancer-related deaths. A significant fraction of prostate tumors are very aggressive, often metastasizing to bone, causing significant morbidity and mortality.
Bucay, Nathan   +4 more
core   +1 more source

Audio-Visual Multimedia Quality Assessment: A Comprehensive Survey

open access: yesIEEE Access, 2017
Measuring perceived quality of audio-visual signals at the end-user has become an important parameter in many multimedia networks and applications. It plays a crucial role in shaping audio-visual processing, compression, transmission and systems, along ...
Zahid Akhtar, Tiago H. Falk
doaj   +1 more source

Alternative polyadenylation of ZEB1 promotes its translation during genotoxic stress in pancreatic cancer cells [PDF]

open access: yes, 2017
Pancreatic ductal adenocarcinoma (PDAC) is characterized by extremely poor prognosis. The standard chemotherapeutic drug, gemcitabine, does not offer significant improvements for PDAC management due to the rapid acquisition of drug resistance by patients.
Bielli, Pamela   +7 more
core   +2 more sources

Low-complexity DOA estimation from short data snapshots for ULA systems using the annihilating filter technique

open access: yesEURASIP Journal on Advances in Signal Processing, 2017
This paper addresses the problem of DOA estimation using uniform linear array (ULA) antenna configurations. We propose a new low-cost method of multiple DOA estimation from very short data snapshots. The new estimator is based on the annihilating filter (
Faouzi Bellili   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy