Results 91 to 100 of about 42,748 (282)
Aggregate, EarlyView.Supramolecular polymerization of porphyrin dyads (PDs) forms kinetically stable nanoparticles (PDParticle) via rapid cooling and thermodynamically stable fibrous polymers (PDFiber) via slow cooling. PDParticle gradually transforms into PDFiber. Introducing chiral alkyl chains induces helicity, with (S)‐PD favoring M helices and (R)‐PD favoring P ...
Hosoowi Lee +6 more
wiley +1 more source
Angewandte Chemie, EarlyView.Chiral aromatic helices of different lengths were prepared, and their nonlinear optical activity was investigated using only linearly polarized incident light. Second‐harmonic scattering studies revealed distinct chiral and achiral contributions to the signal, thereby uncovering an intriguing relationship between the structure of the helices and their ...
Rita Borges‐Anastácio +6 more
wiley +2 more sources
Aggregate, EarlyView.A chiral crystalline metallacyclic membrane is developed via an interfacial coordination self‐assembly of organic and metallic ligands. The ordered metallacyclic membrane exhibits exceptional enantioseparation for racemic mixtures with ultra‐high enantioselectivity (up to 100% enantiomeric excess value) and enhanced permeance.
Run‐Hao Li +3 more
wiley +1 more source
Asian Journal of Organic Chemistry, EarlyView.A facile synthetic route to (−)‐8a‐epi‐lentiginosine from d‐glucose using the Pd‐BiPhePhos catalyzed intramolecular Tsuji–Trost reaction of non−derivatized allylic alcohol as a key construction of the hydroxylated pyrrolidine ring is reported. The crystal structure of (−)‐8a‐epi‐lentiginosne showed the envelope conformation of the five‐membered ring ...
Sunisa Akkarasamiyo +3 more
wiley +1 more source
Photosensitizer Repositioning Affords an Enantiocomplementary Enzyme for [2 + 2]‐Cycloadditions
Angewandte Chemie, EarlyView.In this study, we capitalize on the versatility offered by genetic code expansion to develop a proficient photoenzyme for [2 + 2]‐cycloadditions that is enantiocomplementary to our recently developed photoenzyme EnT1.3. By repositioning the genetically programmed benzophenone photosensitizer and subsequent directed evolution, we have developed an ...
Chuanjie Sun +9 more
wiley +2 more sources
Chiral and Achiral Enantiomeric Separation of (±)-Alprenolol
Open Chemistry, 2019 The chiral separation of enantiomers is crucial for pharmacovigilance within drug discovery. Although a large number of prescribed medications are marketed as pure enantiomers, this is not always the case and many are in fact racemic mixtures.
Guerrero M.M. López +3 more
doaj +1 more source
Enantiopure Chiral Crystals: A Powerful Tool for Absolute Asymmetric Synthesis
Asian Journal of Organic Chemistry, EarlyView.This review covers absolute asymmetric syntheses, which allow the preparation of enantiomerically enriched chiral compounds from achiral precursors. By exploiting the crystallization of certain compounds as a conglomerate, enantiopure chiral crystals are spontaneously obtained.
Jiacheng Li, Valérie Alezra
wiley +1 more source
Unlocking Lactonase Enzymes as Biocatalysts for the Deracemisation of Chiral γ‐Thiolactones
Angewandte Chemie, EarlyView.The application of lactonase enzymes as biocatalysts still remains underexplored. This study discloses the biocatalytic activity of two lactonases in the deracemisation of chiral C3‐substituted‐γ‐thiolactones. The biocatalyst GcL catalyses the enzymatic kinetic resolution (EKR) of C3‐amide‐thiolactones, while the rationally engineered biocatalyst N9 ...
Jingyue Wu +7 more
wiley +2 more sources
Thiophene Containing Polycyclic Aromatic Hydrocarbon Monkey Saddles
Asian Journal of Organic Chemistry, EarlyView.A series of thiophene containing polycyclic aromatic hydrocarbon monkey saddles is presented. The core structure was successfully functionalized to tune the optoelectronic properties and furthermore path the way to use these monkey saddles as building block, for example for oligomeric structures as well as organic cage compounds.
Tobias Kirschbaum +6 more
wiley +1 more source
Asian Journal of Organic Chemistry, EarlyView.Chiral tetraphenylene derivatives possessing helical motifs were developed by linking multiple dibenzopyrrolo[1,2‐a][1,8]naphthyridine units to a tetraphenylene core. These helical motifs adopted helical conformations in solution and exhibited high fluorescence (φ > 0.8).
Kotaro Matsumura +3 more
wiley +1 more source