Results 51 to 60 of about 10,075 (214)
Redox-enabled direct stereoconvergent heteroarylation of simple alcohols
Nature Communications, 2021 Synthesizing complex structures of high enantiomeric excess from racemic feedstock is an enduring challenge. Here, the authors couple racemic secondary alcohols with pyrroles to form enantioenriched 2-substituted heteroarenes, via a borrowing hydrogen ...
Yongbing Liu +4 more
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Novel Chiral Switching Ligands for Enantioselective Asymmetric Reductions of Prochiral Ketones
Molecules, 2001 The newly developed chiral ligands 1 and 4 show opposite enantioselectivity in the asymmetric reduction of prochiral ketones resulting in the production of either enantiomer depending on the metal complex with high enantiomeric excess.
S. Velmathi +3 more
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Chiral symmetry breaking and information accumulation in pre-biological protocell evolution
Scientific ReportsWe study a linear evolutionary model based on the two-dimensional distribution of protocells by total enantiomeric excess and the amount of stored information, which they can pass from generation to generation, and without any mutual inhibition.
Konstantin K. Konstantinov +1 more
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Highly Efficient Lipase-Catalyzed Kinetic Resolution of Chiral Amines
CHIMIA, 1994 The lipase Candida antarctica catalyzes the enantioselective acetylation of chiral primary amines, kinetic resolution leading to an enantiomeric excess (ee) of 90–98%.
Manfred T. Reetz, Claus Dreisbach
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On One Hand: The Optical Sensing of Enantiomeric Excess [PDF]
Chem, 2019 Download : Download high-res image (220KB) Download : Download full-size image Matt graduated from DeMatha Catholic High School in 2005. He earned his BS degree in chemistry at Texas Southern University while simultaneously playing college football. After spending 2 years as a high school chemistry teacher and coach, he decided to deepen
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Prediction of Enantiomeric Excess in a Combinatorial Library of Catalytic Enantioselective Reactions [PDF]
Journal of Combinatorial Chemistry, 2005 A quantitative structure-enantioselectivity relationship was established for a combinatorial library of enantioselective reactions performed by addition of diethyl zinc to benzaldehyde. Chiral catalysts and additives were encoded by their chirality codes and presented as input to neural networks.
João, Aires-de-Sousa, Johann, Gasteiger
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Main Group Metal Chemistry, 2019 We report here the coordination-mediated resolution of methyl o-chloromandelate, which is a key intermediate for clopidogrel, in preparative scale. The reaction of CaO, optically pure (2R, 3R)-O,O′-dibenzoyltartaric acid, and methyl o-chloromandelate in ...
Xu Hong-Wu +4 more
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Hydroformylation of Vinylferrocene with Rhodium and Platinum Catalysts
CHIMIA, 1986 2- and 3-ferrocenylpropionaldehydes (2 and 3) have been prepared by highly regioselective hydroformylation of vinylferrocene (1) using rhodium and platinum catalysts.
László Kollár +2 more
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Photogenerated Oxetanes as a Gateway to Uphill Cyclopropanation
Angewandte Chemie International Edition, EarlyView.An atom‐economical route to densely functionalized cyclopropanes from furans and photochemically activated aldehydes is enabled by a unique oxetane‐to‐cyclopropane rearrangement. These cyclopropanes can be used to access complex bioactive scaffolds and serve as a platform for asymmetric cyclopropane synthesis.
Tim Köglmeier +2 more
wiley +1 more source
Nature Communications, 2016 The Rauhut-Currier reaction is a powerful method to form carbon-carbon bonds. Here, the authors report an enantioselective intramolecular variant between alkenes and allenoates, giving access to highly functionalised bicyclic lactones in excellent ...
Weijun Yao +5 more
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