Results 101 to 110 of about 1,028 (242)
Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis
Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley +2 more sources
A 3D‐printed screening‐to‐reactor platform enabled rapid optimisation of ADH‐200 immobilisation using imidazolium‐based supported ionic liquid phases. High‐throughput evaluation in 96‐well plates identified methyl‐imidazolium formulations as the best‐performing supports, which were directly translated into honeycomb continuous‐flow reactors.
Simone Marchetti +6 more
wiley +1 more source
Advanced Sensor and Detection Materials
The development of sensors at macroscopic or nanometric scales in solid, liquid, or gas phases, contact or noncontact configurations, has driven the research of sensor & detection materials and technology into high gear.
Tiwari, Ashutosh,, Demir, Mustafa M.,
core
Asymmetric Michael addition of cyanide to α,β‐unsaturated aldehydes catalyzed by diarylmethyl‐substituted diphenylprolinol silyl ethers:Thermodynamically controlled product formation under kinetic enantioselective catalysis. Diphenylprolinol silyl ether catalyzed asymmetric Michael/1,2‐addition reaction of cyanide to α,β‐unsaturated aldehydes at high ...
Konstantinos Daskalakis +4 more
wiley +1 more source
Development and Application of Biosensors in the Food Field. [PDF]
Chen R, Zhang S, Li H, Wu L.
europepmc +1 more source
1,1‐and 1,2‐Diborylalkenes: Preparation and Synthetic Applications
In this review, we highlight recent advances in the synthesis and reactivity of 1,1‐diborylalkenes and 1,2‐diborylalkenes, along with various transformations leading to C‐C, C‐heteroatom, and multicomponent products. By providing a comprehensive and practical resource, this review aims to assist researchers in exploring the synthetic utility of 1,1 and
Jayaram Vankudoth +2 more
wiley +1 more source
Monosaccharide-Derived Enantioselectivity in SWCNT Chemoresistive VOC Sensing. [PDF]
Shitrit A +10 more
europepmc +1 more source
A General Strategy for the Synthesis of Jerangolids Enabled by π‐allyl Stille Coupling
A general strategy for the synthesis of jerangolids is established, featuring a late‐stage π‐allyl Stille coupling of two advanced, highly customizable building blocks to form the skipped diene core. The approach provides access to all naturally occurring jerangolids, including jerangolid H, whose configuration is confirmed by NMR analysis.
Janick Schug +2 more
wiley +1 more source
Near-Field Topology-Optimized Superchiral Metasurfaces for Enhanced Chiral Sensing. [PDF]
Jiang Z, Sohag SH, Zhou Y.
europepmc +1 more source
Exploring the potential of β-Cyclodextrin@Ti<sub>3</sub>C<sub>2</sub>T<sub>x</sub> MXene in electrochemical chiral recognition of tyrosine enantiomers. [PDF]
Hasanova S, Gumus E, Akbayrak S, Zor E.
europepmc +1 more source

