In Situ Generated 1:1 Zn(II)-Containing Polymer Complex Sensor for Highly Enantioselective Recognition of N‑Boc-Protected Alanine [PDF]
, 2016 A novel chiral (S)-BINAM-based fluorescence polymer sensor was designed and synthesized by the polymerization of 5,5′-((2,5-dioctyloxy-1,4-phenylene)bis(ethyne-2,1-diyl)bis(2-hydroxy-3-(piperidin-1-ylmethyl)benzaldehyde (M-1) with (S)-2,2 ...
Yixiang Cheng (1424512) +5 more
core +1 more source
A photo-stable fluorescent chiral thiourea probe for enantioselective discrimination of chiral guests [PDF]
, 2018 Herein, a chiral thiourea Schiff base derived from (1R,2R)-1,2-cyclohexanediamine and tetraphenylethylene (TPE) was applied as a highly effective chiral sensor for the enantioselective discrimination of various acids and aminesviaion-pair and hydrogen ...
Shengxin Chen +3 more
core +1 more source
Graphene-based hybrid for enantioselective sensing applications [PDF]
, 2021 Chirality is a major field of research of chemical biology and is essential in pharmacology. Accordingly, approaches for distinguishing between different chiral forms of a compound are of great interest.
Zor, Erhan +5 more
core
Graphene-based hybrid for enantioselective sensing applications [PDF]
, 2017 Chirality is a major field of research of chemical biology and is essential in pharmacology. Accordingly, approaches for distinguishing between different chiral forms of a compound are of great interest.
Zor, Erhan +6 more
core +1 more source
Furo-Fused BINOL Based Crown as a Fluorescent Chiral Sensor for Enantioselective Recognition of Phenylethylamine and Ethyl Ester of Valine [PDF]
, 2016 A furo-fused BINOL based chiral crown was developed as an enantioselective chiral sensor for phenylethylamine and ethyl ester of valine. Fusion of furan to BINOL has resulted in a highly stereo-discriminating backbone for the chiral crown developed. This
Evans C. Coutinho (554348) +3 more
core +1 more source
Enantioselective Recognition of Mandelic Acid by a 3,6-Dithiophen-2-yl-9H-carbazole-Based Chiral Fluorescent Bisboronic Acid Sensor [PDF]
, 2016 We have prepared chiral fluorescent bisboronic acid sensors with 3,6-dithiophen-2-yl-9H-carbazole as the fluorophore. The thiophene moiety was used to extend the π-conjugation framework of the fluorophore in order to red-shift the fluorescence emission ...
Tony D. James (1430470) +3 more
core +1 more source
Angewandte Chemie, EarlyView.An enantioselective rhodium‐catalyzed [2 + 2 + 2] cycloaddition enables the synthesis of axially chiral diaryl ethers. Carbonyl coordination ensures high reactivity and regioselectivity, affording products bearing up to four stereogenic axes with good enantio‐ and diastereoselectivity.
Yu Sato +3 more
wiley +2 more sources
Fluorescence recognition of chiral amino alcohols by using a novel ionic liquid sensor [PDF]
, 2017 A novel task-specific ionic liquid derived from l-phenylalaninol was prepared as an enantioselective fluorescent sensor for the first time.
Xiaoyong Zhao +3 more
core +1 more source
Asymmetric Iron‐Catalyzed Vicinal C(sp3)─H Diamination of Carboxylic Acids
Angewandte Chemie, EarlyView.An iron‐catalyzed vicinal α,β‐C(sp3)─H diamination of readily available carboxylic acids furnishes chiral α,β‐diamino acids in a single pot with high regio‐, diastereo‐, and enantioselectivity (up to >20:1 dr and >99% ee). ABSTRACT The direct construction of chiral 1,2‐diamines through the stereoselective functionalization of two vicinal C(sp3)─H bonds
Bing Zhou +5 more
wiley +2 more sources
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source