Results 41 to 50 of about 1,033 (244)
Angewandte Chemie, EarlyView.Bias‐aware machine learning identified an underexplored imidazolidinone catalyst with broad competitive performance in iminium‐based reactions. Experimental benchmarking shows how data‐driven prioritization can uncover overlooked catalyst scaffolds from sparse and historically biased literature data.
Jiajing Li +4 more
wiley +2 more sources
Advanced Functional Materials, EarlyView.Enhancing crystallinity through thermal annealing leads to amplifying the chiroptical activity of TiO2 nanohelices (NHs) fabricated by glancing angle deposition, ascribed to the suppression of charge trapping. The enhanced chiroptical activity can be converted into pronounced dissymmetric photocatalytic kinetics of circularly polarized photocatalysis ...
Ying Wang +3 more
wiley +1 more source
Redirecting a Native Ene‐Reductase Toward Desaturation With Reverse Enantioselectivity
Angewandte Chemie, EarlyView.A native ene‐reductase, XenA, was repurposed to catalyze the reverse‐enantioselective desaturation of cyclohexanones. The final variant was obtained through extensive protein engineering, combining PROSS‐guided computational design with mutagenesis and screening.
Qing‐Qing Zeng +4 more
wiley +2 more sources
Borylcyclopropanes: Synthetic Strategies and Applications
Angewandte Chemie, EarlyView.Borylcyclopropanes (cyclopropanes bearing a boron substituent) sit at the intersection of two privileged frameworks in synthesis. This review provides the first exhaustive survey of their chemistry, spanning metal–carbene, nucleophilic cyclization, radical, hydroboration, and C─H activation routes, and documenting applications in medicinal chemistry ...
Aiza A. Butt, Joseph M. Ready
wiley +2 more sources
Engineering Homochiral MOFs in TiO2 Nanotubes as Enantioselective Photoelectrochemical Electrode for Chiral Recognition [PDF]
, 2021 Enantioselective sensing of chiral molecules is an important issue for both biomedical research and the pharmaceutical industry. Here, an enantioselective photoelectrochemical (PEC) sensor was constructed by integrating TiO2 nanotubes (NTs) with metal ...
Junli Guo +13 more
core +1 more source
Advanced Science, EarlyView.A one‐step, asymmetric reductive coupling of alkynes and oxa‐ and aza‐bicyclic olefins using a cobalt/photoredox catalytic system through desymmetrization. ABSTRACT Bicyclo[2.2.1]heptane frameworks represent a privileged structural motif prevalent in numerous natural products and bioactive molecules.
Subhankar Pradhan +5 more
wiley +1 more source
Angewandte Chemie, EarlyView.Chiral recognition remains challenging due to minimal property differences. This work develops chiral defective MOFs via linker exchange to enable rapid, direct, luminescent enantioselective sensing, offering a simple, modular strategy that broadens MOF functionality for portable, low‐cost applications in pharmaceuticals, food safety, and environmental
Zongsu Han +8 more
wiley +2 more sources
Advanced Science, EarlyView.We report a palladium‐catalyzed atroposelective cyclization of N‐heterobiaryl triflates with alkynyl boronates to access seven‐membered 1,2‐BN‐bridged biaryls with high yields and excellent enantioselectivity via a cascade DyKAT, cis‐carbopalladation, and 1,2‐migration, which expands the toolbox for axially chiral π‐conjugated boron compounds and opens
Fengya He +6 more
wiley +1 more source
Advanced Science, EarlyView.Tpy–Zn complexes serve as versatile building blocks for the modular assembly of functional materials, including polymers, gels, MOFs, cages, and composites through programmed noncovalent interactions, empowering practical applications in visual molecular recognition, smart functional materials, and photocatalytic transformations. ABSTRACT As one of the
Lixin Duan +4 more
wiley +1 more source
Fluorescent Sensors for the Enantioselective Recognition of Mandelic Acid: Signal Amplification by Dendritic Branching [PDF]
, 2016 Novel chiral bisbinaphthyl compounds have been synthesized for the enantioselective fluorescent recognition of mandelic acid. By introducing dendritic branches to the chiral receptor unit, the fluorescence signals of the receptors are significantly ...
Qiao-Sheng Hu (1650490) +3 more
core +1 more source