Immune- and nonimmune-compartment-specific interferon responses are critical determinants of herpes simplex virus-induced generalized infections and acute liver failure [PDF]
The interferon (IFN) response to viral pathogens is critical for host survival. In humans and mouse models, defects in IFN responses can result in lethal herpes simplex virus 1 (HSV-1) infections, usually from encephalitis.
Leib, David A +3 more
core +3 more sources
A retrospective clinical and epidemiological analysis of cases of hepatitis E in St. Petersburg
Hepatitis E – zoonotic disease that has received a nosological independence twenty years ago, when Russian scientist, Professor M.S. Balayan, identified the pathogen (hepatitis E).
H. D. Peradze +3 more
doaj +1 more source
THE LESIONS OF THE NERVOUS SYSTEM CAUSED BY THE VARICELLA-ZOSTER VIRUS IN CHILDREN
To describe the spectrum of neurological complications in children with varicella and against the background of herpes zoster. The study included children at the age of 0—16 years (n = 84), who recovered from exanthematous form of the disease not longer ...
I. H. Belyaletdinova +3 more
doaj +1 more source
Background In China, there were few studies about the pathogens of acute viral encephalitis and meningitis in children in recent years. The aims of this study were to characterize the etiology and prognosis of acute viral encephalitis and meningitis in ...
Junhong Ai +8 more
doaj +1 more source
The V5A13.1 envelope glycoprotein deletion mutant of mouse hepatitis virus type-4 is neuroattenuated by its reduced rate of spread in the central nervous system. [PDF]
Following intracerebral inoculation of adult Balb/c Byj mice, the MHV-4 strain of mouse hepatitis virus (MHV) had an LD50 of less than 0.1 PFU, whereas its monoclonal antibody resistant variant V5A13.1 had an LD50 of 10(4.2) PFU.
Bloom, F +3 more
core +1 more source
Analysis of tick-borne encephalitis virus-induced host responses in human cells of neuronal origin and interferon-mediated protection [PDF]
Tick-borne encephalitis virus (TBEV) is a member of the genus Flavivirus. It can cause serious infections in humans that may result in encephalitis/meningoencephalitis. Although several studies have described the involvement of specific genes in the host
Grubhoffer, Libor +6 more
core +2 more sources
Envelope-receptor interactions in Nipah virus pathobiology. [PDF]
Nipah (NiV) and Hendra (HeV) viruses are members of the newly defined Henipavirus genus of the Paramyxoviridae. Nipah virus (NiV) is an emergent paramyxovirus that causes fatal encephalitis in up to 70% of infected patients, and there is increasing ...
Lee, Benhur
core +1 more source
Glioblastoma Mimicking Viral Encephalitis Responds to Acyclovir: A Case Series and Literature Review
Viral encephalitis and glioblastoma are both relatively rare conditions with poor prognoses. While the clinical and radiographic presentations of these diseases are often distinctly different, viral encephalitis can sometimes masquerade as glioblastoma ...
Keenan Piper +5 more
doaj +1 more source
Zika virus infection in the returning traveller: what every neurologist should know [PDF]
Zika virus has been associated with a wide range of neurological complications. Neurologists in areas without current active transmission of the virus may be confronted with Zika-associated neurological disease, as a large number of returning travellers ...
Brito Ferreira, Maria Lucia +6 more
core +6 more sources
Viral encephalitis: a practical review on diagnostic approach and treatment
Objectives: To review the diagnostic criteria for encephalitis and encephalopathy of presumed infectious etiology, as well as the diagnostic workup for viral encephalitis and its treatment approaches.
Bruna Klein da Costa +1 more
doaj +3 more sources

