Results 141 to 150 of about 360,434 (351)

Prevalence of Sarcocystis calchasi in free-ranging host species: Accipiter hawks and Common Woodpigeon in Germany [PDF]

open access: yes, 2012
The apicomplexan parasite Sarcocystis calchasi (S. calchasi) triggers pigeon protozoal encephalitis, a neurologic disease in columbids. Accipiter hawks have been identified as the final host, and Columbidae and Psittaciformes as intermediate hosts.
Ciruela, Antonio   +6 more
core   +1 more source

The role of microglia in viral encephalitis: a review

open access: yesJournal of Neuroinflammation, 2019
Viral encephalitis is still very prominent around the world, and traditional antiviral therapies still have shortcomings. Some patients cannot get effective relief or suffer from serious sequelae.
Zhuangzhuang Chen, D. Zhong, Guozhong Li
semanticscholar   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay   +5 more
wiley   +1 more source

Physico-chemical requirements and kinetics of membrane fusion of flavivirus-like particles. [PDF]

open access: yes, 2015
Flaviviruses deliver their RNA genome into the host-cell cytoplasm by fusing their lipid envelope with a cellular membrane. Expression of the flavivirus pre-membrane and envelope glycoprotein genes in the absence of other viral genes results in the ...

core   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale   +5 more
wiley   +1 more source

Encephalitis [PDF]

open access: yesBritish Journal of Hospital Medicine, 2019
Frackowiak, Marta   +2 more
openaire   +2 more sources

A score that predicts 1-year functional status in patients with anti-NMDA receptor encephalitis

open access: yesNeurology, 2018
Objective To construct a grading score that predicts neurologic function 1 year after diagnosis of anti-NMDA receptor (NMDAR) encephalitis. Methods Three hundred eighty-two patients with detailed information and functional status at 1 year were studied ...
R. Balu   +5 more
semanticscholar   +1 more source

The evolving therapeutic landscape of spinal muscular atrophy – A scoping review of investigational agents, emerging delivery technologies and strategic innovations

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić   +7 more
wiley   +1 more source

A novel biomimetic liposome drug delivery system mediated by macrophage targeting for precision treatment of encephalitis

open access: yesBMEMat, EarlyView.
An advanced macrophage‐mediated biomimetic liposome (AC‐LP@RAW) that can penetrate the BBB and precisely target inflammatory sites in the deep brain was established in this study based on the unique immune homing property of macrophages, and showed a significantly improved delivery of curcumin to the brain.
Mengru Wu   +5 more
wiley   +1 more source

Encephalitis diagnosis using metagenomics: application of next generation sequencing for undiagnosed cases

open access: yesJournal of Infection, 2018
Background Current estimates suggest that even in the most resourced settings, the aetiology of encephalitis is identified in less than half of clinical cases. It is acknowledged that filling this gap needs a combination of rigorous sampling and improved
Julianne R. Brown   +2 more
semanticscholar   +1 more source

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