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Pathobiology of Japanese encephalitis virus infection
Molecular Aspects of Medicine, 2021Japanese encephalitis virus (JEV) is a flavivirus, spread by the bite of carrier Culex mosquitoes. The subsequent disease caused is Japanese encephalitis (JE), which is the leading global cause of virus-induced encephalitis. The disease is predominant in the entire Asia-Pacific region with the potential of global spread.
Kiran Bala Sharma +2 more
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2020
Viruses belonging to the genus Flavivirus of the family Flaviviridae are the established human pathogens and their zoonotic potential has escalated in the last few decades. They are transmitted by vectors and accordingly grouped as tick-borne flaviviruses and mosquito-borne flaviviruses.
Samir Das +3 more
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Viruses belonging to the genus Flavivirus of the family Flaviviridae are the established human pathogens and their zoonotic potential has escalated in the last few decades. They are transmitted by vectors and accordingly grouped as tick-borne flaviviruses and mosquito-borne flaviviruses.
Samir Das +3 more
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Japanese encephalitis virus infection
2014Japanese encephalitis (JE) is a viral encephalitis caused by Japanese encephalitis virus (JEV), a single stranded positive sense RNA virus of the genus Flavivirus. The reservoir of JEV is wild birds and pigs; it is spread to humans by mosquitoes. There are approximately 68,000 cases and 15,000 deaths per year.
Michael J, Griffiths +2 more
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Neuropathogenesis of Japanese Encephalitis Virus
Journal of Neurovirology, 2002In the central nervous system, the Japanese encephalitis virus can replicate only in neurons. The mechanism of the type of neurotropism was analyzed. The susceptibility to Japanese encephalitis virus infection in the rat brain was closely associated with neuronal immaturity.
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Agglutination of Japanese encephalitis virus with concanavalin A
Journal of Virology, 1975Results of experiments have indicated that reduction in biological activities at high concentrations of Japanese encephalitis virus is caused by aggregates of the virus by concanavalin A. The possibility exists that the concanavalin A binding site is different from hemagglutination and antireceptor sites of Japanese encephalitis virus.
Y, Yoshinaka, T, Shiomi
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Japanese Encephalitis Virus-Infected Cells
2023RNA virus infections have been a leading cause of pandemics. Aided by global warming and increased connectivity, their threat is likely to increase over time. The flaviviruses are one such RNA virus family, and its prototypes such as the Japanese encephalitis virus (JEV), Dengue virus, Zika virus, West Nile virus, etc., pose a significant health burden
Kiran Bala, Sharma +2 more
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Transplacental Infection with Japanese Encephalitis Virus
Journal of Infectious Diseases, 1980During a widespread epidemic of Japanese encephalitis, five pregnant women affected by the illness were observed. The diagnosis of Japanese encephalitis virus (JEV) infection was established on the basis of clinical presentation, rising titers of hemagglutination-inhibiting antibody, and the presence of specific IgM antibodies.
U C, Chaturvedi +5 more
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Japanese Encephalitis Virus: Ecology and Epidemiology
2002Japanese encephalitis (JE) virus is a mosquito-borne zoonotic flavivirus that infects a wide range of vertebrate species in an enzootic cycle primarily of large waterfowl birds and swine. Horses and humans are considered bystanders to this enzootic cycle and, once infected, dead-end hosts.
T P, Endy, A, Nisalak
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Effect of current Japanese encephalitis vaccine on different strains of Japanese encephalitis virus
Vaccine, 1987Inactivated Japanese encephalitis (JE) vaccine was given to healthy children and their neutralizing antibody titres against nine JE virus strains were measured. After two shots of the vaccine in the first year, most of the children showed seroconversion, but their neutralizing antibody titres were not high, and one year after vaccination their titres ...
Y, Okuno +4 more
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Ecology and Geographical Expansion of Japanese Encephalitis Virus
Annual Review of Entomology, 2009Japanese encephalitis virus (JEV) (Flavivirus: Flaviviridae) is a leading cause of encephalitis in eastern and southern Asia. The virus is maintained in a zoonotic cycle between ardeid wading birds and/or pigs and Culex mosquitoes. The primary mosquito vector of JEV is Culex tritaeniorhynchus, although species such as Cx. gelidus, Cx. fuscocephala, and
Van Den Hurk, A. +2 more
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