Results 141 to 150 of about 61,946 (270)
The FEBS Journal, EarlyView.Human RNase 7 is known to exert antimicrobial activity in epithelial tissues. Here, using SH‐SY5Y and U‐87 MG, neuroblastoma and glioblastoma cell lines, respectively, we found that RNase 7 enhances immune responses to LPS stimulation by reducing the expression of pro‐inflammatory cytokines, nitric oxide, and ROS.
Rosanna Culurciello +9 more
wiley +1 more source
When to consider an inborn error of immunity: clues for physicians
Internal Medicine Journal, EarlyView.Abstract The term inborn errors of immunity (IEIs) refers to the rapidly expanding group of genetic disorders causing dysregulation of the immune system. With improved genetic testing in recent years, the number of defined IEIs and their range of phenotypic presentations has grown vastly, with more than 550 IEIs now described.
Meera Thangarajah, Lucinda J. Berglund
wiley +1 more source
Targeting progressive multiple sclerosis: Toward mechanism‐informed precision medicine
Journal of Internal Medicine, EarlyView.Abstract Multiple sclerosis has undergone a therapeutic revolution over the past three decades. Randomized clinical trials and real‐world data demonstrate that modern disease‐modifying therapies substantially reduce relapse rates and acute inflammatory activity detected by magnetic resonance imaging (MRI).
Fredrik Piehl +3 more
wiley +1 more source
Journal of Sleep Research, EarlyView.ABSTRACT Emerging evidence links COVID‐19 to the predisposition of Parkinson's disease (PD). However, the relationship between long COVID and prodromal PD‐like features remains unclear, particularly in long COVID participants with dream‐enactment behaviours (DEBs) that may be suggestive of possible REM sleep behaviour disorder.
Siyi Gong +28 more
wiley +1 more source
Climate Suitability and Risk of Japanese Encephalitis and Murray Valley Encephalitis Viruses During Outbreak and Non-Outbreak Years in Temperate Regions of Australia [PDF]
Climate Suitability and Risk of Japanese Encephalitis and Murray Valley Encephalitis Viruses During Outbreak and Non-Outbreak Years in Temperate Regions of ...
Robert Faggian (13091460) +2 more
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COVID‐19–Induced Narcolepsy Type I With Cataplexy: A Short Report
Journal of Sleep Research, EarlyView.ABSTRACT Narcolepsy type I is a rare neurological sleep disorder characterised by chronic excessive daytime sleepiness, cataplexy, and low orexin (hypocretin) levels. Infection with SARS‐CoV‐2 has been linked to neurological and neuropsychiatric sequelae, but cases of post‐COVID narcolepsy remain extremely uncommon.
Torsten Vinding Merinder +2 more
wiley +1 more source
Medical and Veterinary Entomology, EarlyView.Mosquitoes in Eastern Ontario, Canada, readily fed on bloodmeal hosts consistent with patterns observed in other regions of North America. Enzootic and bridge vector mosquitoes fed on amplification hosts like American Robins (Turdus migratorius) together with humans, highlighting a potential route for WNV and EEEV transmission to human populations. Our
Colton R. A. Stephens +5 more
wiley +1 more source
, 1997 Patients with viral infections of the central nervous system are encountered daily, but it is often difficult to establish a correct differential diagnosis. This paper attempts to ‘’reorganize” our knowledge of such infections.
Kambas, I, Andreula, CF, Marano, G
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Come together: Data sharing to support one health responses to vector‐borne disease threats
Medical and Veterinary Entomology, EarlyView.A One Health framework integrating diverse data across human, animal and environmental sectors is essential for effective surveillance and response is vital for responding to vector‐borne disease risks. Communities adopting global data standards, depositing data in shared repositories, and responsible data use can significantly improve VBD data ...
Francis Windram +36 more
wiley +1 more source
Effect of blood meals and mating on biodemographic characteristics of Aedes albopictus
Physiological Entomology, EarlyView.Lifespan did not differ between virgin and mated males and females. The number of blood meals (one and two) significantly reduced adult lifespan compared with those with no blood meal. The effect of the second blood meal doubled females' egg production and their reproductive output.
Georgios D. Mastronikolos +1 more
wiley +1 more source