Results 151 to 160 of about 92,152 (260)

Increased Numbers of CD4+ T‐Cells in the Hypocretin/Orexin Region of Narcolepsy Type 1

Annals of Neurology, Volume 99, Issue 5, Page 1173-1178, May 2026.
Narcolepsy type 1 (NT1) is presumed to be an autoimmune disorder caused by hypothalamic loss of hypocretin (Hcrt; orexin). In postmortem NT1 brains, we observed an 11‐fold increase of CD4+ T‐cells in the Hcrt region compared with control hypothalami, without a corresponding rise in CD8+ T‐cells.
Ling Shan, Milo Fonville, Mabel Hoekstra, Rolf Fronczek, Joost Smolders, Dick F. Swaab   +5 more
wiley   +1 more source

Herpes Zoster Vaccine Awareness and Uptake Among Older Adults in Saudi Arabia: Insights for Public Health, Preventive Medicine, and Primary Care Practice

Journal of General and Family Medicine, Volume 27, Issue 3, May 2026.
ABSTRACT Background/Objectives Complications from Herpes Zoster (HZ) are common among older adults and immunosuppressed populations. The HZ vaccine is a clinically and financially superior alternative to antiviral medications. However, a knowledge gap exists within the population regarding HZ and the vaccine.
Adam F. Aldhawyan, Mohammed A. BuSaad, Hasan M. Alswiket, Abdullah M. Alradhi, Ryad F. Alamry, Fadel A. Almulla, Amjad Z. Boarish, Reema J. Alghamdi, Abdullatif K. Althunyan, Amani M. AlQarni   +9 more
wiley   +1 more source

Nonclassical MHC‐I Molecules: Emerging Therapeutic Targets in Next‐Generation Immunotherapy

MedComm, Volume 7, Issue 5, May 2026.
Immunotherapies dependent on classical MHC‐I molecules face significant challenges, including extreme polymorphism and frequent downregulation in pathological conditions. This review discusses how nonclassical MHC‐I molecules (HLA‐E, HLA‐F, HLA‐G, CD1, MR1) may potentially circumvent these limitations through restricted genetic diversity, stable ...
Wanlin He, Andrew J. McMichael
wiley   +1 more source

Human Cytomegalovirus Infection in Haematopoietic Stem Cell Transplant Recipients and CAR T Cell Recipients – PART 1: Risk Factors, Clinical Impact and Immune Response

Reviews in Medical Virology, Volume 36, Issue 3, May 2026.
ABSTRACT Human cytomegalovirus (HCMV) is one of the most important opportunistic pathogens in immunocompromised individuals, including allogeneic haematopoietic stem cell transplant (allo‐HSCT) recipients. In allo‐HSCT, HCMV seropositivity of the recipient and donor is associated with inferior survival outcomes, and post‐transplant HCMV reactivation is
Danya Kaplan, Emily Blyth, Gaurav Sutrave, Michelle K. Yong, David J. Gottlieb, Allison Abendroth, Barry Slobedman, Lauren Stern   +7 more
wiley   +1 more source

Evaluation of Selected Brain Damage Biomarkers in the Determination of Brain Damage in Dogs With Neurological Distemper

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
In this study, a significant increase in serum NSE, GFAP, CK‐B, IgM and IgM concentrations was determined in dogs with nervous distemper. It was shown that NSE, GFAP and CK‐B biomarkers have a useful and reliable diagnostic value in determining brain damage in dogs with nervous distemper .
Muhammed Mustafa Kapar, Mahmut Ok, Oğuzhan Avcı   +2 more
wiley   +1 more source

Investigation of the Seroprevalence of Lentivirus ovivismae and Lentivirus capartenc (Formerly Known as Maedi‐Visna and Caprine Arthritis‐Encephalitis Virus) Infections in Sheep and Goats in the Yozgat Region

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
This study conducted in the Yozgat region determined a prevalence of 6.35% for maedi‐visna in sheep and 17.5% for caprine arthritis encephalitis in goats, providing critical data for small ruminant health and disease management in the area. ABSTRACT Background Lentivirus ovivismae and Lentivirus capartenc (formerly maedi‐visna and caprine arthritis ...
Emre Sayar, Secil Sevinc Temizkan, Akın Kırbaş, Güvenç Gökalp   +3 more
wiley   +1 more source

Neurological Disorders in Dogs: A Retrospective Analysis of Prevalence, Aetiology, Lesion Locations, and Regional Variations in Northeastern Iran

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
This retrospective study evaluated 422 dogs with neurological disorders among 9131 canine referrals over 8.5 years in northeastern Iran. Infectious diseases, particularly canine distemper (33.2%), were the leading cause, followed by trauma and idiopathic conditions. The prosencephalon was the most frequently affected anatomical region.
Ali Behrouzian, Ali Asghar Sarchahi, Hadi Jabbari Noghabi   +2 more
wiley   +1 more source

LRP8 is an entry receptor for tick-borne encephalitis viruses. [PDF]

Proc Natl Acad Sci U S A
Li P, Hui S, Chong Z, Escaffre O, Nguyen MN, Muraro SP, Janova H, Ma H, Cao S, Kaszuba T, Imbiakha B, Palakurty S, Pearson ML, Price DA, Amarasinghe GK, Leung DW, Rossi SL, Freiberg AN, Fremont DH, Diamond MS.   +19 more
europepmc   +1 more source

Efficacy of a ML336 derivative against Venezuelan and eastern equine encephalitis viruses. [PDF]

Antiviral Res, 2019
Jonsson CB, Cao X, Lee J, Gabbard JD, Chu YK, Fitzpatrick EA, Julander J, Chung DH, Stabenow J, Golden JE.   +9 more
europepmc   +1 more source

Vaccination and transfusion safety at the time of expanding use of live attenuated vaccines

Vox Sanguinis, EarlyView.
Pierre Tiberghien, Pierre Gallian, Virginie de La Taille, Caroline Bacquet, Syria Laperche   +4 more
wiley   +1 more source