Results 41 to 50 of about 92,152 (260)

Flaviviruses—Induced Neurological Sequelae

Pathogens
Flaviviruses, a group of single-stranded RNA viruses spread by mosquitoes or ticks, include several significant neurotropic viruses, such as West Nile virus (WNV), Japanese encephalitis virus (JEV), tick-borne encephalitis virus (TBEV), and Zika virus ...
Samantha Gabrielle Cody, Awadalkareem Adam, Andrei Siniavin, Sam S. Kang, Tian Wang   +4 more
doaj   +1 more source

Life‐Threatening Bradycardia in Anti‐NMDA‐Receptor Encephalitis and a Novel Use for Permanent Pacing

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Pediatric anti‐NMDA receptor encephalitis (pNMDARE) is an autoantibody‐mediated disorder that can cause severe autonomic dysfunction, including symptomatic bradycardia and asystole. Dysautonomia can last for years, making it very challenging to manage.
Sarah Tucker, Abhijit Das, Andres Jimenez, Areeba Basit, Yike Jiang, Emily A. Smitherman, Heather Van Mater, Taylor Howard, Alexander J. Sandweiss, Kristen S. Fisher   +9 more
wiley   +1 more source

Neutralizing Antibodies against California Serogroup Orthobunyaviruses in Human Serum Samples, Montana, USA

Emerging Infectious Diseases
Viral encephalitis is often underreported and undiagnosed. To understand the potential causes of viral encephalitis in the state of Montana, USA, we examined the relative incidence of human infections for the California serogroup (CSG) of ...
Tyson A. Woods, Stephen F. Johnson, Alyssa B. Evans, Karin E. Peterson   +3 more
doaj   +1 more source

Powassan Virus Infection Detected by Metagenomic Next-Generation Sequencing, Ohio, USA

Emerging Infectious Diseases, 2023
We describe a 4-year-old male patient in Ohio, USA, who had encephalitis caused by Powassan virus lineage 2. Virus was detected by using metagenomic next-generation sequencing and confirmed with IgM and plaque reduction neutralization assays. Clinicians
Marjorie Farrington, Jamie Elenz, Matthew Ginsberg, Charles Y. Chiu, Steve Miller, Scott F. Pangonis   +5 more
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Surveillance of Viral Encephalitis in the Context of COVID-19: A One-Year Observational Study among Hospitalized Patients in Dakar, Senegal

Viruses, 2022
The burden of encephalitis and its associated viral etiology is poorly described in Africa. Moreover, neurological manifestations of COVID-19 are increasingly reported in many countries, but less so in Africa.
Jamil Kahwagi, Al Ousseynou Seye, Ahmadou Bamba Mbodji, Rokhaya Diagne, El hadji Mbengue, Maouly Fall, Soa Fy Andriamandimby, Ava Easton, Martin Faye, Gamou Fall, Ndongo Dia, Babacar Ndiaye, Momo Banda Ndiaye, Alle Gueye, Serigne Saliou Mbacke, Fatou Kane, Mohamed Inejih El Ghouriechy, ENSENE Investigators, Lala Bouna Seck, Ndiaga Matar Gaye, Amadou Alpha Sall, Moustapha Ndiaye, Ousmane Faye, Amadou Gallo Diop, Jean-Michel Heraud   +24 more
doaj   +1 more source

Clinical perspectives of emerging pathogens in bleeding disorders. [PDF]

, 2006
As a result of immunological and nucleic-acid screening of plasma donations for transfusion-transmissible viruses, and the incorporation of viral reduction processes during plasma fractionation, coagulation-factor concentrates (CFC) are now judged safe ...
Bozzette, Samuel, Diamond, Michael, Koerper, Marion A, Kulkarni, Roshni, Ludlam, Christopher A, Powderly, William G, Ritchie, Bruce, Siegel, Jamie, Simmonds, Peter, Stanley, Samuel, Tapper, Michael L, von Depka, Mario   +11 more
core   +1 more source

Pitfalls associated with the use of molecular diagnostic panels in the diagnosis of cryptococcal meningitis [PDF]

, 2017
We report the case of a kidney transplantation patient on chronic immunosuppressive therapy presenting with subacute meningitis. The final diagnosis of cryptococcal meningitis was delayed due to 2 false-negative cryptococcal results on a molecular ...
Burnham, Carey-Ann, Dubberke, Erik, Franklin, Alexander, Lainhart, William, O\u27Halloran, Jane A, Powderly, William   +5 more
core   +2 more sources

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Molecular characterization of viruses associated with encephalitis in São Paulo, Brazil.

PLoS ONE, 2019
The objective of this study was to characterize the prevalence of viral encephalitis due to arbovirus infection of the Togaviridae and Flaviviridae families in São Paulo, Brazil.
Jerenice E Ferreira, Suzete C Ferreira, Cesar Almeida-Neto, Anna S Nishiya, Cecilia S Alencar, Gisele R Gouveia, Helio Caiaffa-Filho, Helio Gomes, Raimunda Telma de Macedo Santos, Steven S Witkin, Alfredo Mendrone-Junior, Ester C Sabino   +11 more
doaj   +1 more source