Results 91 to 100 of about 126,056 (280)

Impaired Treg‐Mediated Immune Regulation in Peri‐Implantitis Lesions and Implant Loss: Insights From Histological and Molecular Analyses

open access: yesJournal of Clinical Periodontology, EarlyView.
ABSTRACT Aim To evaluate the T regulatory lymphocyte (Treg) profile and its potential contribution to peri‐implant tissue destruction during peri‐implantitis (PI). Methods PI granulation tissue and crevicular fluid collected during PI surgical (PI group, n = 23) and explantation (PI‐X group, n = 23) therapy, with peri‐implant healthy tissue from second‐
Emilio A. Cafferata   +6 more
wiley   +1 more source

Fatal Human Case of Western Equine Encephalitis, Uruguay

open access: yesEmerging Infectious Diseases, 2011
Adriana Delfraro   +8 more
doaj   +1 more source

A Camelid-Derived STAT-Specific Nanobody Inhibits Neuroinflammation and Ameliorates Experimental Autoimmune Encephalomyelitis (EAE)

open access: yesCells
Proinflammatory T-lymphocytes recruited into the brain and spinal cord mediate multiple sclerosis (MS) and currently there is no cure for MS. IFN-γ-producing Th1 cells induce ascending paralysis in the spinal cord while IL-17-producing Th17 cells mediate
Evaristus C. Mbanefo   +7 more
doaj   +1 more source

Neurological manifestations of chronic graft versus host disease. [PDF]

open access: yesIntern Med J
Abstract Introduction Allogeneic haemopoietic stem cell transplant (allo‐HSCT) is an established therapy for many malignant and non‐malignant conditions, with an increasing number of uses and indications in recent decades. Complications including graft versus host disease (GvHD) carry significant morbidity and mortality.
Koren T   +7 more
europepmc   +2 more sources

Sympathetic innervation of human cervical lymph nodes: A potential neuroimmunomodulatory target for the treatment of T‐cell‐driven autoimmune diseases like MS?

open access: yesJournal of Anatomy, EarlyView.
Recent animal studies have shown that the sympathetic nervous system (SNS) prevents disease activity of EAE (Experimental autoimmune encephalomyelitis, animal model of Multiple Sclerosis [MS]), presumably through adrenergic activity in the deep cervical lymph nodes (DCLNs).
Christopher Kremer   +4 more
wiley   +1 more source

Anti‐Inflammatory Macrophage‐Derived Exosomes Modified With Self‐Antigen Peptides for Treatment of Experimental Autoimmune Encephalomyelitis

open access: yesAdvanced Science
Current treatments for autoimmune diseases often involve broad‐acting immunosuppressants, which carry risks such as infections and malignancies. This study investigates whether exosomes derived from anti‐inflammatory macrophages (AE) and decorated with ...
Qiaoyun Li   +5 more
doaj   +1 more source

Functional impairments and disability profile of CNS non-MS inflammatory demyelinating diseases: A hospital-based study

open access: yesJournal of Medical and Scientific Research
Background: Non-MS CNS inflammatory demyelinating diseases are pathologically primary demyelination caused by immunological injury to oligodendrocytes and as a result are clinically severe and can present either as clinically isolated syndromes or ...
Noor M   +11 more
doaj   +1 more source

Phenolic compounds in species of the Blechnaceae

open access: yesPlant Biology, EarlyView.
The occurrence of caffeic acid derivatives in 32 species of Blechnaceae revealed differences in the presence of rosmarinic acid and blechnic acid B, a novel compound in ferns. Abstract Rosmarinic acid and other caffeic and 4‐coumaric acid derivatives are widespread in land plants.
M. Ufland, M. Petersen
wiley   +1 more source

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